Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 4/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219988 | 0.83 | CTSK (0.42) | MAPK1CTSKCTSS | |
| SCHEMBL7219744 | 0.77 | KCNH2 (0.42) | NOS2ALDH1A1L3MBTL1HPGDKDM4E | |
| SCHEMBL7215618 | 0.72 | HPGD (0.42) | NOS2ALDH1A1L3MBTL1HPGDKDM4E | |
| SCHEMBL7219740 | 0.72 | NOS2 (0.46) | NOS2ALDH1A1ESR1ESR2MAPK1 | |
| SCHEMBL7215442 | 0.69 | L3MBTL1 (0.40) | NOS2ALDH1A1L3MBTL1HPGDKDM4E | |
| SCHEMBL7213427 | 0.69 | GABRP (0.40) | NOS2ALDH1A1L3MBTL1HPGDKDM4E | |
| SCHEMBL27781329 | 0.68 | HPGD (0.41) | ALDH1A1L3MBTL1HPGDKDM4ENPSR1 | |
| SCHEMBL7213414 | 0.67 | L3MBTL1 (0.34) | ALDH1A1L3MBTL1HPGDKDM4ENPSR1 | |
| SCHEMBL433374 | 0.67 | NOS2 (0.74) | NOS2ESR1ESR2 | |
| SCHEMBL1187597 | 0.67 | NOS2 (0.57) | NOS2HPGDNPSR1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |