Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 7/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215435 | 0.75 | L3MBTL1 (0.39) | L3MBTL1MEN1KMT2AKDM5AKDM4C | |
| SCHEMBL16389813 | 0.72 | NOS3 (0.36) | MEN1KMT2AALDH1A1LMNANOS3 | |
| SCHEMBL7219988 | 0.71 | CTSK (0.42) | KDM5AMAPK1 | |
| SCHEMBL7219805 | 0.69 | NOS2 (0.42) | L3MBTL1KDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL16968393 | 0.68 | PGK1 (0.47) | L3MBTL1MEN1KMT2AKDM5AKDM4C | |
| SCHEMBL7215701 | 0.68 | HPGD (0.36) | L3MBTL1MEN1KMT2AKDM5AKDM4C | |
| SCHEMBL9347463 | 0.67 | PDE3B (0.41) | KMT2AKDM5AKDM4EALDH1A1LMNA | |
| SCHEMBL7215604 | 0.67 | CYP2A6 (0.43) | MEN1KMT2ANOS3NOS2 | |
| SCHEMBL2156767 | 0.67 | L3MBTL1 (0.35) | L3MBTL1MEN1KMT2AKDM5AKDM4C | |
| SCHEMBL27455608 | 0.67 | KDM5A (0.38) | L3MBTL1MEN1KMT2AKDM5AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603007-B1 | Intermediates in the fields of pharmaceuticals, agrichemicals, ligands, silver halide photosensitive materials, liquid crystals, surfactants, electrophotography and organic electroluminescence | SANKIO CHEMICAL CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1231207-A1 | NOVEL BIPYRIDYL DERIVATIVES | Sankio Chemical Co., Ltd. (JP) | 2002-08-14 | — | — | EP | disclosed |