SCHEMBL722370

SCHEMBL722370

CC(C)OC[C@H](N)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.50
SLC1A3 P43003 5/20 0.45
SLC1A2 P43004 5/20 0.45
SLC1A1 P43005 4/20 0.45
NOS3 P29474 1/20 0.43
NOS1 P29475 1/20 0.43
NOS2 P35228 1/20 0.43
PTGS1 P23219 1/20 0.42
SLC7A11 Q9UPY5 1/20 0.42
GRIK1 P39086 5/20 0.39
GRIA2 P42262 3/20 0.39
GRIA4 P48058 3/20 0.39
GRIK3 Q13003 3/20 0.39
GRIK5 Q16478 3/20 0.39
GRIK2 Q13002 3/20 0.39
GRIA1 P42261 2/20 0.39
GRM8 O00222 1/20 0.39
GRM6 O15303 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10436302 1.00 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2SLC1A1NOS3
SCHEMBL20932872 1.00 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2SLC1A1NOS3
Hydrochloric Acid SCHEMBL23111921 0.98 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1NOS3
SCHEMBL1252077 0.86 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2SLC1A1NOS3
SCHEMBL7138120 0.84 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1NOS3
SCHEMBL28603100 0.84 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1NOS3
SCHEMBL25867906 0.84 GABRP (0.33) SLC7A5SLC1A3SLC1A2SLC1A1NOS3
SCHEMBL25660617 0.81 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2SLC1A1GRIK1
SCHEMBL15368912 0.81 TSHR (0.35) SLC7A5SLC1A3SLC1A2SLC1A1NOS3
SCHEMBL14036911 0.81 SLC7A5 (0.34) SLC7A5SLC1A3SLC1A2SLC1A1NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724459-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Peptidream Inc (JP) 2026-04-15 EP disclosed
EP-4724457-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Rayzebio, Inc. (US) 2026-04-15 EP disclosed
WO-2024254339-A9 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2025-10-16 WO disclosed
US-20250263365-A1 O-SUBSTITUTED SERINE DERIVATIVE PRODUCTION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-08-21 US disclosed
EP-3878836-B1 O-SUBSTITUTED SERINE DERIVATIVE PRODUCTION METHOD CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-07-23 EP disclosed
US-12312297-B2 O-substituted serine derivative production method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-05-27 US disclosed
WO-2024252336-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF PEPTIDREAM INC. (JP) 2024-12-12 WO disclosed
WO-2024254339-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2024-12-12 WO disclosed
US-11732008-B2 Preparation of functional homocysteine residues in polypeptides and peptides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-08-22 US disclosed
US-11732008-B2 Preparation of functional homocysteine residues in polypeptides and peptides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-08-22 US disclosed
US-20190119322-A1 PREPARATION OF FUNCTIONAL HOMOCYSTEINE RESIDUES IN POLYPEPTIDES AND PEPTIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-04-25 US disclosed
US-8759318-B2 Phosphoramidate derivatives of guanosine nucleoside compounds for treatment of viral infections INHIBITEX, INC. (US) 2014-06-24 US disclosed
WO-2012048013-A2 PHOSPHORODIAMIDATE DERIVATIVES OF GUANOSINE NUCLEOSIDE COMPOUNDS FOR TREATMENT OF VIRAL INJECTIONS INHIBITEX, INC. (US) 2012-04-12 WO disclosed
US-20120052046-A1 Phosphoramidate Derivatives of Guanosine Nucleoside Compunds for Treatment of Viral Infections UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2012-03-01 US disclosed
EP-2385951-A2 PHOSPHORAMIDATE DERIVATIVES OF GUANOSINE NUCLEOSIDE COMPOUNDS FOR TREATMENT OF VIRAL INFECTIONS University College Cardiff Consultants, Ltd. (GB) 2011-11-16 EP disclosed
US-20110254856-A1 MOBILE TERMINAL AND METHOD OF CONTROLLING OPERATION OF THE MOBILE TERMINAL LG ELECTRONICS INC. (KR) 2011-10-20 US disclosed
WO-2010081082-A2 PHOSPHORAMIDATE DERIVATIVES OF GUANOSINE NUCLEOSIDE COMPOUNDS FOR TREATMENT OF VIRAL INFECTIONS UNIVERSITY COLLEGE OF CARDIFF CONSULTANTS LIMITED (GB) 2010-07-15 WO disclosed
CN-101098852-A Glycogen phosphorylase inhibitor compounds and pharmaceutical compositions thereof SMITHKLINE BEECHAM CORP (US) 2008-01-02 CN disclosed
EP-0353211-A1 New compounds Aktiebolaget Hässle (SE) 1990-01-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190119322-A1 PREPARATION OF FUNCTIONAL HOMOCYSTEINE RESIDUES IN POLYPEPTIDES AND PEPTIDES BHMT2, BHMT, PTMS SLC7A5 159/4885SLC1A3 707/4885SLC1A2 963/4885
US-20120052046-A1 Phosphoramidate Derivatives of Guanosine Nucleoside Compunds for Treatment of Viral Infections PNP, SAMHD1, MTAP SLC7A5 907/4885SLC1A3 2260/4885SLC1A2 2880/4885
US-20250263365-A1 O-SUBSTITUTED SERINE DERIVATIVE PRODUCTION METHOD STS, SMOX, TST SLC7A5 431/4885SLC1A3 832/4885SLC1A2 1457/4885
US-11732008-B2 Preparation of functional homocysteine residues in polypeptides and peptides BHMT2, BHMT, PTMS SLC7A5 159/4885SLC1A3 707/4885SLC1A2 963/4885
US-12312297-B2 O-substituted serine derivative production method STS, SMOX, TST SLC7A5 431/4885SLC1A3 832/4885SLC1A2 1457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.