Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | MGAM | O43451 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SI | P14410 | 2/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ULK1 | O75385 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7230688 | 0.88 | AKT1 (0.44) | AKT1SLC6A3MGAMGAASI | |
| SCHEMBL7230583 | 0.85 | FAAH (0.44) | SLC6A3FAAHCES1 | |
| SCHEMBL7223707 | 0.85 | NPC1 (0.38) | AKT1MGAMGAASIMGAM2 | |
| SCHEMBL7232903 | 0.85 | SLC6A3 (0.38) | AKT1SLC6A3MGAMGAASI | |
| SCHEMBL7224822 | 0.85 | CHRNA7 (0.47) | AKT1CHRNB2CHRNA7CHRNA4FAAH | |
| SCHEMBL7230437 | 0.82 | SLC9A1 (0.42) | AKT1SLC6A3GAACHRNB2CHRNA4 | |
| SCHEMBL7224267 | 0.82 | NPC1 (0.39) | AKT1MGAMGAASIMGAM2 | |
| SCHEMBL7223511 | 0.82 | S1PR2 (0.48) | SLC6A3MGAMGAASIMGAM2 | |
| SCHEMBL7231940 | 0.82 | GAA (0.46) | SLC6A3MGAMGAASIMGAM2 | |
| SCHEMBL7226398 | 0.82 | AKT1 (0.34) | AKT1SLC6A3CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | claimed |
| US-6562816-B2 | Alpha 7 nicotine acetylcholine receptor agonist anti-psychotic agent, with reduced side effects | PHARMACIA & UPJOHN COMPANY | 2003-05-13 | — | — | US | disclosed |