SCHEMBL722603

SCHEMBL722603

Fc1c2nc(cc3ccc(cc4nc(cc5ccc1[nH]5)C=C4)[nH]3)C=C2

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.50
▸ STAT1 P42224 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL868308 0.95 STAT3 (0.48) STAT3STAT1
SCHEMBL7877923 0.86 STAT3 (0.42) STAT3STAT1
SCHEMBL1290623 0.84 STAT3 (0.56) STAT3STAT1
SCHEMBL79329 0.83 STAT3 (0.50) STAT3STAT1
SCHEMBL51570 0.82 STAT3 (0.59) STAT3STAT1
Hydrochloric Acid SCHEMBL5596534 0.82 STAT3 (0.53) STAT3STAT1
SCHEMBL19206150 0.82 STAT3 (0.53) STAT3STAT1
SCHEMBL9866324 0.82 STAT3 (0.49) STAT3STAT1
SCHEMBL6479855 0.82 STAT3 (0.49) STAT3STAT1
SCHEMBL38329 0.82 STAT3 (0.49) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119409914-A Fluorine-containing porphyrin-based covalent organic framework, and preparation method and application thereof 海南师范大学 2025-02-11 — — CN claimed
CN-115155532-B Polyfluoroporphyrin covalent organic framework magnetic nanosphere and preparation method and application thereof 武汉工程大学 2024-04-26 — — CN claimed
CN-115155532-A Polyfluorinated porphyrin covalent organic framework magnetic nanosphere and preparation method and application thereof 武汉工程大学 2022-10-11 — — CN claimed
CN-119409914-A Fluorine-containing porphyrin-based covalent organic framework, and preparation method and application thereof 海南师范大学 2025-02-11 — — CN disclosed
CN-118613471-A Fluorochemical and contrast agent TDK株式会社 2024-09-06 — — CN disclosed
CN-115155532-B Polyfluoroporphyrin covalent organic framework magnetic nanosphere and preparation method and application thereof 武汉工程大学 2024-04-26 — — CN disclosed
CN-115155532-B Polyfluoroporphyrin covalent organic framework magnetic nanosphere and preparation method and application thereof 武汉工程大学 2024-04-26 — — CN disclosed
US-20240027480-A1 METHOD OF ANALYZING DILUTED BIOLOGICAL SAMPLE COMPONENT LEISURE, INC. (JP) 2024-01-25 — — US disclosed
US-11808776-B2 Method of analyzing diluted biological sample component LEISURE, INC. (JP) 2023-11-07 — — US disclosed
US-11808777-B2 Method of analyzing diluted biological sample component LEISURE, INC. (JP) 2023-11-07 — — US disclosed
CN-116333037-A Thiol-containing peptides and fluoroporphyrins coupled as biological probes 化学与精细化工广东省实验室 2023-06-27 — — CN disclosed
US-6951640-B2 Use of novel metalloporphyrins as imageable tumor-targeting agents for radiation therapy BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) 2005-10-04 — — US disclosed
CN-1159317-C Meso-tetra (2,5-difluorophenyl) porphyrin containing fluoroporphyrin developer, its synthesis and application 华东师范大学 2004-07-28 — — CN disclosed
US-6759403-B2 PORPHYRINS CONTAINING MULTIPLE CARBORANE CAGES WHICH SELECTIVELY ACCUMULATE IN NEOPLASTIC TISSUE WITHIN THE IRRADIATION VOLUME; ANTICANCER AGENTS BROOKHAVEN SCIENCE ASSOCIATES, LLC 2004-07-06 — — US disclosed
US-20030165426-A1 Use of novel metalloporphyrins as imageable tumor-targeting agents for radiation therapy UNITED STATES DEPARTMENT OF ENERGY 2003-09-04 — — US disclosed
US-6566517-B2 Halogenated derivatives of boronated porphyrins containing multiple carborane cages; can be used in cancer therapies including, but not limited to, boron neutron-capture therapy and photodynamic therapy. BROOKHAVEN SCIENCE ASSOCIATES, LLC 2003-05-20 — — US disclosed
US-20030083494-A1 Novel metalloporphyrins and their uses as radiosensitizers for radiation therapy UNITED STATES DEPARTMENT OF ENERGY 2003-05-01 — — US disclosed
US-20030032799-A1 Novel metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy ENERGY, UNITED STATES DEPARTMENT OF 2003-02-13 — — US disclosed
CN-1394861-A Meso-tetra (2,5-difluorophenyl) porphyrin containing fluoroporphyrin developer, its synthesis and application UNIV HUADONG (CN) 2003-02-05 — — CN disclosed
US-5268371-A Derivatives of porphyrin and metalloporphyrins optionally coupled to a biologically active molecule and pharmaceutical composition containing them CIS BIO INTERNATIONAL (FR) 1993-12-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030165426-A1 Use of novel metalloporphyrins as imageable tumor-targeting agents for radiation therapy PPOX, TFRC, SLC40A1 STAT3 2069/4885STAT1 3188/4885
US-20030032799-A1 Novel metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy PPOX, SLC39A14, SLC40A1 STAT3 2149/4885STAT1 3188/4885
US-20030083494-A1 Novel metalloporphyrins and their uses as radiosensitizers for radiation therapy PPOX, SLC39A14, HMBS STAT3 2054/4885STAT1 2589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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