Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 8/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.40 |
| ▸ | GLS | O94925 | 4/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998311 | 0.93 | GLS (0.44) | MAPK8GLSKDM4EALDH1A1GAA | |
| SCHEMBL8094494 | 0.90 | MAPK8 (0.44) | MAPK8GLSALDH1A1 | |
| SCHEMBL7994626 | 0.90 | GLS (0.42) | MAPK8GLSCA12CA1CA2 | |
| SCHEMBL7233873 | 0.86 | MAPK8 (0.54) | MAPK8MAPK9MAPK10GLSNOD2 | |
| SCHEMBL8069562 | 0.86 | MAPK8 (0.47) | MAPK8MAPK9MAPK10GLSKDM4E | |
| SCHEMBL8104093 | 0.85 | KMT2A (0.49) | MAPK8HTTALDH1A1GAA | |
| SCHEMBL8094581 | 0.84 | SMN1; SMN2 (0.40) | MAPK8ROCK2MAPK9MAPK10CA12 | |
| SCHEMBL7232438 | 0.82 | GLS (0.43) | MAPK8GLSKDM4EALDH1A1GAA | |
| SCHEMBL7735892 | 0.80 | RAB9A (0.46) | MAPK8MAPK10KDM4EALDH1A1GAA | |
| SCHEMBL7230936 | 0.78 | GAA (0.47) | MAPK8CA1CA2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991631-A1 | SUBSTITUTED AMINOHETEROCYCLYLAMIDES | Bayer Aktiengesellschaft (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000375-A1 | SUBSTITUTED AMINOHETEROCYCLYLAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-07 | — | — | WO | disclosed |