Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723147 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRTDP1POLB | |
| SCHEMBL724233 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRTDP1POLB | |
| SCHEMBL11428771 | 0.76 | CLTC (0.50) | ALDH1A1TSHRTDP1POLBKMT2A | |
| SCHEMBL27726655 | 0.71 | TSHR (0.46) | ALDH1A1LMNATSHRTDP1POLB | |
| SCHEMBL3895684 | 0.70 | CLTC (0.46) | ALDH1A1TSHRTDP1POLBKMT2A | |
| SCHEMBL23909557 | 0.69 | ALDH1A1 (0.54) | ALDH1A1LMNAPKMTSHRTDP1 | |
| SCHEMBL2083961 | 0.68 | TSHR (0.60) | ALDH1A1TSHRTDP1POLBKMT2A | |
| SCHEMBL11505795 | 0.68 | PTPN1 (0.47) | ALDH1A1TSHRTDP1POLBKMT2A | |
| SCHEMBL28823837 | 0.67 | PTPN1 (0.59) | ALDH1A1TSHRTDP1POLBKMT2A | |
| SCHEMBL24837592 | 0.67 | CLTC (0.47) | ALDH1A1TSHRTDP1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140127137-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | Cercacor Laboratories, Inc (US) | 2014-05-08 | — | — | US | disclosed |
| US-8466286-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | CERCACOR LABORATORIES, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| US-20120052018-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | MASIMO LABORATORIES, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-8029765-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | MASIMO LABORATORIES, INC. (US) | 2011-10-04 | — | — | US | disclosed |
| US-8008088-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | MASIMO LABORATORIES, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-20090004108-A1 | Smmr (Small Molecule Metabolite Reporters) For Use As In Vivo Glucose Biosensors | MASIMO LABORATORIES, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| US-20070110672-A1 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | CERCACOR LABORATORIES, INC. | 2007-05-17 | — | — | US | disclosed |
| WO-2005065241-A2 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | ARGOSE, INC. (US) | 2005-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140127137-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | GCKR, SYMPK, SUCNR1 | ALDH1A1 4364/4885LMNA 1967/4885PKM 423/4885 |
| US-20070110672-A1 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | GCKR, SYMPK, SUCNR1 | ALDH1A1 4364/4885LMNA 1967/4885PKM 423/4885 |
| US-20120052018-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | GCKR, SYMPK, SUCNR1 | ALDH1A1 4364/4885LMNA 1967/4885PKM 423/4885 |
| US-20090004108-A1 | Smmr (Small Molecule Metabolite Reporters) For Use As In Vivo Glucose Biosensors | GCKR, SYMPK, SUCNR1 | ALDH1A1 4364/4885LMNA 1967/4885PKM 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.