Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7238456 | 0.87 | XIAP (0.34) | PTGER2 | |
| SCHEMBL67697 | 0.78 | MEN1 (0.42) | SIRT2PTGER2FAAH | |
| SCHEMBL7246524 | 0.72 | CHRNB2 (0.30) | — | |
| SCHEMBL3511520 | 0.72 | FAAH (0.36) | SIRT2PTGER2FAAH | |
| SCHEMBL5342536 | 0.71 | MEN1 (0.33) | SIRT2FAAH | |
| SCHEMBL14558307 | 0.70 | MAPT (0.32) | SIRT2 | |
| SCHEMBL7498162 | 0.70 | HTR7 (0.41) | — | |
| SCHEMBL6631239 | 0.70 | SIRT2 (0.32) | SIRT2 | |
| SCHEMBL5337903 | 0.69 | CHRNB2 (0.31) | SIRT2 | |
| SCHEMBL3669973 | 0.68 | HPGD (0.40) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6645990-B2 | For prophylaxis and therapy of diseases, such as cell proliferation or apoptosis mediated diseases | AMGEN INC. | 2003-11-11 | — | — | US | disclosed |
| US-20020193405-A1 | Thiazolyl urea compounds and methods of uses | AMGEN INC. | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193405-A1 | Thiazolyl urea compounds and methods of uses | SLC14A1, UMPS, BAX | SIRT2 1006/4885PTGER2 4077/4885FAAH 3791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.