SCHEMBL72425

SCHEMBL72425

NNC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPO P05164 2/20 0.67
CYP3A4 P08684 2/20 0.67
KDM5A P29375 1/20 0.67
BLM P54132 1/20 0.67
GFER P55789 1/20 0.67
PMP22 Q01453 1/20 0.67
HIF1A Q16665 1/20 0.67
MAPT P10636 4/20 0.64
ALDH1A1 P00352 4/20 0.64
KDM4E B2RXH2 3/20 0.64
L3MBTL1 Q9Y468 2/20 0.64
OGG1 O15527 1/20 0.64
LMNA P02545 1/20 0.64
TSHR P16473 2/20 0.60
TP53 P04637 1/20 0.60
CYP1A2 P05177 1/20 0.58
ADORA3 P0DMS8 1/20 0.58
CYP2D6 P10635 1/20 0.58
CYP2A6 P11509 1/20 0.58
CYP2C19 P33261 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL11861447 0.93 TSHR (0.61) MPOCYP3A4KDM5ABLMGFER
SCHEMBL9386909 0.93 MPO (0.59) MPOCYP3A4KDM5ABLMGFER
SCHEMBL2678949 0.89 MPO (0.80) MPOCYP3A4KDM5ABLMGFER
SCHEMBL343630 0.89 MPO (0.80) MPOCYP3A4KDM5ABLMGFER
SCHEMBL2834402 0.88 MITF (0.68) MPOCYP3A4KDM5ABLMGFER
SCHEMBL28188923 0.87 MPO (0.76) MPOCYP3A4KDM5ABLMGFER
Isoniazid SCHEMBL28210298 0.85 KDM4E (0.84) MPOCYP3A4KDM5ABLMGFER
Terephthalic Acid SCHEMBL998372 0.82 TSHR (0.63) MAPTALDH1A1TSHRTP53CYP2C19
SCHEMBL752600 0.82 MPO (0.70) MPOCYP3A4KDM5ABLMGFER
Benzoic Acid Hydrazide SCHEMBL4515671 0.82 CYP3A4 (0.62) MPOCYP3A4KDM5ABLMGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325117-B Terbium coordination covalent organic framework fluorescent material and preparation method and application thereof 南昌市检验检测中心 2024-08-20 CN claimed
CN-118325117-A Terbium coordination covalent organic framework fluorescent material and preparation method and application thereof 南昌市检验检测中心 2024-07-12 CN claimed
US-20220304304-A1 Compositions of Dicarboxylic Acid Derivatives UPL LTD (IN) 2022-09-29 US claimed
CN-115093524-A Two-dimensional mesoporous acylhydrazone type COF material and preparation method and application thereof 南昌大学 2022-09-23 CN claimed
CN-114071998-A Composition of dicarboxylic acid derivatives UPL有限公司 2022-02-18 CN claimed
CN-114044899-A Preparation method of modified aromatic poly-1, 3, 4-oxadiazole and film thereof 上海工程技术大学 2022-02-15 CN claimed
WO-2020254902-A1 COMPOSITIONS OF DICARBOXYLIC ACID DERIVATIVES UPL LIMITED (IN) 2020-12-24 WO claimed
EP-3747266-A1 COMPOSITIONS OF DICARBOXYLIC ACID DERIVATIVES UPL Corporation Limited (MU) 2020-12-09 EP claimed
EP-3105597-B1 OXIDIZED LIPID DETECTION KRATOS ANALYTICAL LTD (GB) 2020-11-18 EP claimed
US-20030105140-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2003-06-05 US claimed
WO-2002102301-A2 SUBSTITUTED INDOLE-2-CARBOXYLIC ACID BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF CYTOVIA, INC. (US) 2002-12-27 WO claimed
US-20020128292-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof CYTOVIA, INC. 2002-09-12 US claimed
US-12509544-B2 Aqueous binder formulation BASF SE (DE) 2025-12-30 US disclosed
US-12134695-B2 Aqueous binder formulation based on functionalized polyurethanes BASF SE (DE) 2024-11-05 US disclosed
CN-118325117-B Terbium coordination covalent organic framework fluorescent material and preparation method and application thereof 南昌市检验检测中心 2024-08-20 CN disclosed
CN-118325117-B Terbium coordination covalent organic framework fluorescent material and preparation method and application thereof 南昌市检验检测中心 2024-08-20 CN disclosed
US-4211860-A N,N*-BISMALEIMIDE TECHNOCHEMIE GMBH VERFAHRENSTECHNIK (DE) 1980-07-08 US disclosed
US-4110375-A INTERMEDIATES HOECHST AKTIENGESELLSCHAFT (DE) 1978-08-29 US disclosed
US-4064349-A INTERMEDIATES HOECHST AKTIENGESELLSCHAFT (DT) 1977-12-20 US disclosed
US-3944522-A P-PHENYLENE TEREPHTHALAMIDE, TEREPHTHAL HYDRAZIDE, AND P-BENZAMIDE TORAY INDUSTRIES, INC. (JA) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128292-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof BAD, API5, CASP2 MPO 2665/4885CYP3A4 1159/4885KDM5A 2065/4885
US-20030105140-A1 Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof BAD, API5, CASP2 MPO 2665/4885CYP3A4 1159/4885KDM5A 2065/4885
US-12509544-B2 Aqueous binder formulation ADH1C, AKR1C1, AKR1C2 MPO 2515/4885CYP3A4 1529/4885KDM5A 521/4885
US-20220304304-A1 Compositions of Dicarboxylic Acid Derivatives MDH2, MDH1, DLST MPO 2963/4885CYP3A4 4280/4885KDM5A 252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.