Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 5/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27561375 | 0.73 | CA2 (0.42) | BRD4PTGS1PTGS2 | |
| SCHEMBL27564358 | 0.73 | PTGS1 (0.43) | MAPTATMPOLBPTGS1PTGS2 | |
| SCHEMBL14414981 | 0.72 | KAT2B (0.55) | MAPTATMPOLBKAT2B | |
| SCHEMBL11233535 | 0.71 | PTGS1 (0.55) | POLBPTGS1PTGS2KAT2B | |
| SCHEMBL27582055 | 0.70 | P2RX7 (0.39) | POLB | |
| SCHEMBL27564357 | 0.69 | ALDH3A1 (0.46) | MAPTKMT2ANPC1 | |
| SCHEMBL27561385 | 0.69 | TDP1 (0.38) | MAPTPTGS1PTGS2CCNT1CDK9 | |
| SCHEMBL27582103 | 0.69 | KDR (0.40) | MAPTKMT2ANPC1BRAF | |
| SCHEMBL4164692 | 0.67 | KAT2B (0.46) | MAPTATMTNIKKAT2B | |
| SCHEMBL14757815 | 0.67 | KAT2B (0.46) | MAPTATMPTGS1PTGS2KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670357-B2 | Antiinflammatory agents | BRISTOL-MYERS SQUIBB COMPANY | 2003-12-30 | — | — | US | disclosed |