Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7673427 | 0.87 | CCR2 (0.52) | ALDH1A1MAPTMEN1KMT2AALOX12 | |
| SCHEMBL7663530 | 0.86 | ALDH1A1 (0.59) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7248361 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7664079 | 0.79 | ATM (0.53) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL7248655 | 0.77 | SLC40A1 (0.45) | ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL30958859 | 0.76 | CYP2C9 (0.56) | ALDH1A1MAPTLMNAPOLBL3MBTL1 | |
| SCHEMBL1200176 | 0.75 | ACLY (0.64) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL8993697 | 0.73 | ALDH1A1 (0.78) | ALDH1A1MAPTMEN1KMT2AALOX12 | |
| SCHEMBL1200313 | 0.72 | HPGD (0.80) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL8993799 | 0.72 | ALDH1A1 (0.76) | ALDH1A1MAPTMEN1KMT2AALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562840-B1 | Non-peptidic inhibitors of proteolytic enzymes such as urokinase | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-05-13 | — | — | US | disclosed |
| US-6492403-B1 | TREATING SYMPTOMS OF ACUTE OR CHRONIC DISORDER MEDIATED BY CLASSICAL PATHWAY OF COMPLEMENT CASCADE; PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | disclosed |