Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | IL1RN | P18510 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7247948 | 0.86 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HPGDGAAKMT2A | |
| SCHEMBL7673427 | 0.85 | CCR2 (0.52) | ALDH1A1SMN1; SMN2HPGDKMT2ATSHR | |
| SCHEMBL7248361 | 0.84 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HPGDKMT2AHTT | |
| SCHEMBL7664079 | 0.83 | ATM (0.53) | ALDH1A1SMN1; SMN2GAAKMT2APOLB | |
| SCHEMBL7248655 | 0.81 | SLC40A1 (0.45) | ALDH1A1SLC40A1PKM | |
| SCHEMBL7665091 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HPGDKMT2AGLO1KDM4E | |
| SCHEMBL7663217 | 0.77 | HCRTR1 (0.49) | TSHRKEAP1RECQLMAPT | |
| SCHEMBL7248579 | 0.76 | ALDH1A1 (0.52) | ALDH1A1GAAKMT2AHTTPKM | |
| SCHEMBL13744463 | 0.73 | IL1RN (0.46) | ALDH1A1SMN1; SMN2GAAKMT2AIL1RN | |
| SCHEMBL532975 | 0.73 | ACLY (0.69) | ALDH1A1HPGDGAAKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492403-B1 | TREATING SYMPTOMS OF ACUTE OR CHRONIC DISORDER MEDIATED BY CLASSICAL PATHWAY OF COMPLEMENT CASCADE; PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | disclosed |