Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PKLR | P30613 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663530 | 0.83 | ALDH1A1 (0.59) | KMT2AMEN1GLO1PKMLMNA | |
| SCHEMBL7248361 | 0.80 | ALDH1A1 (0.49) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7247948 | 0.79 | ALDH1A1 (0.51) | KMT2AMEN1L3MBTL1TDP1LMNA | |
| SCHEMBL7673427 | 0.78 | CCR2 (0.52) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7663217 | 0.76 | HCRTR1 (0.49) | PGRPGAM1 | |
| SCHEMBL2747035 | 0.76 | ACLY (0.62) | KMT2AMEN1TDP1GLO1LMNA | |
| SCHEMBL2748864 | 0.76 | LMNA (0.71) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL6928674 | 0.76 | C1S (0.69) | KMT2AMEN1PLAU | |
| SCHEMBL7248655 | 0.74 | SLC40A1 (0.45) | L3MBTL1TDP1PKMALDH1A1 | |
| SCHEMBL7666030 | 0.74 | C1S (0.43) | KMT2AMEN1L3MBTL1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492403-B1 | TREATING SYMPTOMS OF ACUTE OR CHRONIC DISORDER MEDIATED BY CLASSICAL PATHWAY OF COMPLEMENT CASCADE; PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | disclosed |