SCHEMBL7255673

SCHEMBL7255673

CC1CCOC(C)(c2cccc(O)c2)O1

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 8/20 0.41
OPRD1 P41143 5/20 0.41
OPRM1 P35372 6/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5339706 0.81 OPRD1 (0.49) OPRK1OPRD1OPRM1
SCHEMBL9501274 0.72 RXRA (0.44)
SCHEMBL10888704 0.72 CA2 (0.37)
SCHEMBL28980719 0.69 OPRK1 (0.43) OPRK1OPRD1OPRM1
SCHEMBL31206949 0.67 OPRM1 (0.61) OPRK1OPRD1OPRM1
SCHEMBL11155431 0.66 OPRK1 (0.51) OPRK1OPRD1OPRM1
SCHEMBL22781618 0.66 DRD2 (0.43)
SCHEMBL10839765 0.65 ESR2 (0.41)
SCHEMBL9138011 0.65 OPRD1 (0.63) OPRK1OPRD1OPRM1
SCHEMBL9229582 0.65 OPRK1 (0.41) OPRK1OPRD1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003070714-A1 FLUOROUS ACETYLATION UNISEARCH LIMITED (AU) 2003-08-28 WO claimed