Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256570 | 0.69 | PDE4B (0.46) | PTGS2PDE4BLMNAHSP90AA1HSP90AB1 | |
| SCHEMBL5032009 | 0.67 | CRHBP (0.41) | PTGS2PDE4BLMNACRHBPCRHR2 | |
| SCHEMBL6569636 | 0.66 | ALDH1A1 (0.40) | PTGS2PDE4BLMNAHSP90AA1HSP90AB1 | |
| SCHEMBL1089399 | 0.66 | LMNA (0.43) | PTGS2PDE4BLMNACRHBPCRHR2 | |
| SCHEMBL7255688 | 0.66 | PTGS2 (0.48) | PTGS2PDE4BLMNAHSP90AA1HSP90AB1 | |
| SCHEMBL4942933 | 0.65 | SMN1; SMN2 (0.38) | PTGS2PDE4BLMNAP2RX7ALDH1A1 | |
| SCHEMBL22012817 | 0.65 | SMN1; SMN2 (0.38) | PTGS2PDE4BLMNAP2RX7ALDH1A1 | |
| SCHEMBL6348979 | 0.65 | PTGS2 (0.71) | PTGS2PDE4BLMNAHSP90AA1HSP90AB1 | |
| SCHEMBL22666802 | 0.64 | PTGS2 (0.45) | PTGS2PDE4BLMNAHSP90AA1HSP90AB1 | |
| SCHEMBL11089344 | 0.63 | NR3C1 (0.42) | PTGS2PDE4BLMNANPSR1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080553-A1 | CYCLOPENTENE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2003-10-02 | — | — | WO | disclosed |