Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258192 | 0.80 | ADRA2A (0.42) | ADRA2ACA1CA2ADRA1A | |
| SCHEMBL20810855 | 0.79 | ADRA2A (0.43) | ADRA2ACA1CA2HTR6ADRA1A | |
| SCHEMBL1878272 | 0.75 | IDO1 (0.50) | CA1CA2HTR6 | |
| SCHEMBL29617530 | 0.75 | IDO1 (0.50) | CA1CA2HTR6 | |
| SCHEMBL7258318 | 0.74 | HTR6 (0.34) | CA1CA2HTR6 | |
| SCHEMBL7327615 | 0.74 | ADRA2A (0.51) | ADRA2ACA1CA2GID4HSD17B2 | |
| SCHEMBL7012015 | 0.73 | ADRA2A (0.50) | ADRA2ACA1CA2GID4HSD17B2 | |
| SCHEMBL7258183 | 0.71 | SIRT1 (0.47) | ADRA2AGID4HSD17B2 | |
| SCHEMBL24539163 | 0.69 | ADRA2A (0.47) | ADRA2ACA1CA2GID4HSD17B2 | |
| SCHEMBL8370650 | 0.68 | HSD17B2 (0.56) | ADRA2ACA1CA2HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614898-B1 | INDOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-6291470-B1 | DELTA-OPIOID ANTAGONIST HAVING HIGH SELECTIVITY AND ACTIVITY, THAT EXHIBITS IMMUNOSUPPRESSIVE ACTION, ANTIALLERGIC ACTION, ANTI-INFLAMMATORY ACTION AND BRAIN CELL-PROTECTING ACTION | TORAY INDUSTRIES, INC. (JP) | 2001-09-18 | — | — | US | disclosed |
| US-6087369-A | AN IMMUNOSUPPRESSIVE AGENT, ANTIALLERGIC AGENT, ANTI-INFLAMMATORY AGENT AND BRAIN CELL-PROTECTING AGENT | TORAY INDUSTRIES, LTD. (JP) | 2000-07-11 | — | — | US | disclosed |
| US-5852030-A | Indole derivatives, process for producing the same and medicinal uses of the same | TORAY INDUSTRIES, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| EP-0614898-A1 | INDOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1994-09-14 | — | — | EP | disclosed |