Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.37 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453006 | 0.86 | NPC1 (0.40) | ALDH1A1MAPTMAOA | |
| SCHEMBL7258751 | 0.84 | ATM (0.40) | LMNANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7263594 | 0.82 | RAB9A (0.43) | LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7264011 | 0.81 | MCHR1 (0.39) | LMNAMCHR1NPSR1ALDH1A1MAPT | |
| SCHEMBL7258922 | 0.81 | MRGPRX4 (0.42) | MAPTMAOA | |
| SCHEMBL7449950 | 0.80 | ALDH1A1 (0.41) | LMNAALDH1A1MAPT | |
| SCHEMBL7263297 | 0.80 | KMT2A (0.43) | — | |
| SCHEMBL7449714 | 0.79 | MMP9 (0.38) | MAPT | |
| SCHEMBL7448681 | 0.79 | KMT2A (0.40) | LMNASMN1; SMN2 | |
| SCHEMBL7548111 | 0.78 | MMP9 (0.35) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |