Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453006 | 0.86 | NPC1 (0.40) | KMT2A | |
| SCHEMBL7263594 | 0.83 | RAB9A (0.43) | CYP3A4 | |
| SCHEMBL7258751 | 0.83 | ATM (0.40) | KMT2A | |
| SCHEMBL7258922 | 0.81 | MRGPRX4 (0.42) | — | |
| SCHEMBL7264011 | 0.80 | MCHR1 (0.39) | — | |
| SCHEMBL7259588 | 0.80 | LMNA (0.44) | — | |
| SCHEMBL7449714 | 0.78 | MMP9 (0.38) | — | |
| SCHEMBL7448681 | 0.78 | KMT2A (0.40) | KMT2A | |
| SCHEMBL7449950 | 0.77 | ALDH1A1 (0.41) | KMT2A | |
| SCHEMBL7548111 | 0.77 | MMP9 (0.35) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |