Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GPR132 | Q9UNW8 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ADA | P00813 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453006 | 0.93 | NPC1 (0.40) | MRGPRX4NPC1RAB9AMAOAMAPT | |
| SCHEMBL7263594 | 0.86 | RAB9A (0.43) | NPC1RAB9AMAPTPPARGPPARA | |
| SCHEMBL7258751 | 0.84 | ATM (0.40) | MRGPRX4NPC1RAB9APPARGPPARA | |
| SCHEMBL7263297 | 0.81 | KMT2A (0.43) | — | |
| SCHEMBL7264011 | 0.81 | MCHR1 (0.39) | MAPT | |
| SCHEMBL7259588 | 0.81 | LMNA (0.44) | MAOAMAPT | |
| SCHEMBL7449714 | 0.79 | MMP9 (0.38) | MAPT | |
| SCHEMBL7448681 | 0.79 | KMT2A (0.40) | — | |
| SCHEMBL7449950 | 0.78 | ALDH1A1 (0.41) | MRGPRX4MAPT | |
| SCHEMBL7548111 | 0.78 | MMP9 (0.35) | NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | disclosed |