Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 3/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 3/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263206 | 0.82 | PDGFRA (0.47) | PDGFRAPDGFRBALDH1A1FGFR2KIT | |
| SCHEMBL7258379 | 0.81 | FGFR2 (0.44) | PDGFRAPDGFRBALDH1A1MAPK1HTT | |
| SCHEMBL7258836 | 0.79 | KDM4E (0.52) | PDGFRAPDGFRBALDH1A1HTTFGFR2 | |
| SCHEMBL2099937 | 0.79 | ALDH1A1 (0.63) | PDGFRAPDGFRBALDH1A1MAPK1HTT | |
| SCHEMBL7263674 | 0.78 | THRB (0.44) | PDGFRAPDGFRBMAPK1HTTFGFR2 | |
| SCHEMBL7258432 | 0.77 | TUBB1 (0.46) | PDGFRAPDGFRBALDH1A1L3MBTL1FGFR2 | |
| SCHEMBL11015595 | 0.76 | CA12 (0.65) | ALDH1A1MAPK1HTTL3MBTL1TTR | |
| SCHEMBL6694977 | 0.75 | L3MBTL1 (0.42) | PDGFRAPDGFRBALDH1A1MAPK1HTT | |
| SCHEMBL11646840 | 0.74 | LTA4H (0.61) | PDGFRAPDGFRBALDH1A1MAPK1HTT | |
| SCHEMBL7262915 | 0.73 | AKR1C3 (0.51) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003094845-A2 | PYRIDINE-BASED THYROID RECEPTOR LIGANDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-11-20 | — | — | WO | disclosed |