Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD3 | Q99594 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 5/20 | 0.32 |
| ▸ | TK2 | O00142 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282618 | 0.88 | ALDH1A1 (0.34) | MEN1GAAKMT2AFAAHCHRNB4 | |
| SCHEMBL7275231 | 0.86 | CHRNB4 (0.37) | MEN1KMT2AELANECHRM3FAAH | |
| SCHEMBL7275948 | 0.86 | CHRNB4 (0.37) | MEN1KMT2AELANECHRM3FAAH | |
| SCHEMBL7281843 | 0.86 | EHMT2 (0.35) | KMT2AMAPTDUT | |
| SCHEMBL7276617 | 0.85 | FAAH (0.37) | MEN1KMT2AELANECHRM3FAAH | |
| SCHEMBL7283123 | 0.83 | TEAD3 (0.42) | TEAD3MEN1GAAKMT2AMAPT | |
| SCHEMBL7275003 | 0.83 | ELANE (0.37) | TEAD3GAAMAPTLTA4HELANE | |
| SCHEMBL7283379 | 0.83 | SSTR5 (0.41) | MEN1KMT2ALTA4HCHRNB4CHRNA3 | |
| SCHEMBL7274552 | 0.82 | TK1 (0.34) | TEAD3TK2 | |
| SCHEMBL7273697 | 0.80 | HRH3 (0.34) | ELANECHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |