Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28989038 | 0.92 | LSS (0.54) | LSSLTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8539691 | 0.89 | LSS (0.59) | LSSLTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8536500 | 0.88 | KCNA3 (0.58) | LSSLTA4HHRH3KCNH2HRH1 | |
| SCHEMBL53853 | 0.86 | KCNA3 (0.67) | LTA4HCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL10803113 | 0.86 | LSS (0.64) | LSSLTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL16893707 | 0.86 | HDAC1 (0.58) | LSSHRH3KCNH2HRH1KCNA3 | |
| SCHEMBL5571444 | 0.86 | HDAC1 (0.58) | LSSHRH3KCNH2HRH1KCNA3 | |
| SCHEMBL6748834 | 0.86 | HDAC1 (0.58) | LSSHRH3KCNH2HRH1KCNA3 | |
| SCHEMBL16893888 | 0.86 | HDAC1 (0.58) | LSSHRH3KCNH2HRH1KCNA3 | |
| SCHEMBL6509588 | 0.86 | HDAC1 (0.58) | LSSHRH3KCNH2HRH1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11952450-B2 | Compound for encapsulation film and composition thereof, and film, organic light-emitting device and encapsulation method | JILIN OLED OPTICAL AND ELECTRONIC MATERIALS CO., LTD. (CN) | 2024-04-09 | — | — | US | claimed |
| CN-115216178-B | Ink composition for OLED packaging and preparation method thereof | 西安思摩威新材料有限公司 | 2023-11-28 | — | — | CN | claimed |
| CN-115216178-A | Ink composition for OLED packaging and preparation method thereof | 西安思摩威新材料有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-114957314-A | Compound for film packaging, composition, packaging film and film packaging structure | 吉林奥来德光电材料股份有限公司 | 2022-08-30 | — | — | CN | claimed |
| US-20220259352-A1 | Compound for encapsulation film and composition thereof, and film, organic light-emitting device and encapsulation method | JILIN OLED OPTICAL AND ELECTRONIC MATERIALS CO., LTD. (CN) | 2022-08-18 | — | — | US | claimed |
| US-6903090-B2 | Such as 10-(2-ethoxyphenyl)-1,2,3,4,5,6-hexahydroazepino(4,5-b)indole; for treatment of anxiety, depression, schizophrenia, epilepsy, migraine, Alzheimers disease, sleep disorders, obesity, stress related diseases, and/or drug withdrawal | PFIZER (US) | 2005-06-07 | — | — | US | claimed |
| US-6828314-B2 | Modulation of the activity of serotonin receptors (5-HT) to treat diseases such as anxiety, depression or obesity | PFIZER | 2004-12-07 | — | — | US | claimed |
| US-20030225058-A1 | Substituted azepino[4,5b]indoline derivatives | PHARMACIA & UPJOHN COMPANY | 2003-12-04 | — | — | US | claimed |
| US-20030220321-A1 | Substituted azepino[4,5b]indole derivatives | PHARMACIA & UPJOHN COMPANY | 2003-11-27 | — | — | US | claimed |
| EP-1319005-A2 | SUBSTITUTED AZEPINO[4,5-B]INDOLINE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2003-06-18 | — | — | EP | claimed |
| EP-1319004-A2 | SUBSTITUTED AZEPINO[4,5-B]INDOLE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2003-06-18 | — | — | EP | claimed |
| US-20020107278-A1 | Substituted azepino[4,5b]indole derivatives | PHARMACIA & UPJOHN COMPANY | 2002-08-08 | — | — | US | claimed |
| US-20020077318-A1 | Substituted azepino[4,5b] indoline derivatives | PHARMACIA & UPJOHN COMPANY | 2002-06-20 | — | — | US | claimed |
| WO-2002024701-A2 | SUBSTITUTED AZEPINO[4,5B)INDOLE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2002-03-28 | — | — | WO | claimed |
| WO-2002024700-A2 | SUBSTITUTED AZEPINO[4,5b]INDOLINE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2002-03-28 | — | — | WO | claimed |
| EP-3998252-B1 | THIOL COMPOUNDS, SYNTHESIS METHOD THEREFOR, AND UTILIZATION OF SAID THIOL COMPOUNDS | SHIKOKU CHEM (JP) | 2024-04-24 | — | — | EP | disclosed |
| US-11952450-B2 | Compound for encapsulation film and composition thereof, and film, organic light-emitting device and encapsulation method | JILIN OLED OPTICAL AND ELECTRONIC MATERIALS CO., LTD. (CN) | 2024-04-09 | — | — | US | disclosed |
| WO-2001004118-A2 | QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 RECEPTOR LIGANDS | ALMIRALL PRODESFARMA S.A. (ES) | 2001-01-18 | — | — | WO | disclosed |
| US-5719155-A | CARDIOVASCULAR DISORDERS | JAPAN TOBACCO INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107278-A1 | Substituted azepino[4,5b]indole derivatives | HTR5A, HTR1A, HTR1E | LSS 1332/4885LTA4H 1066/4885CHRNB2 201/4885 |
| US-20220259352-A1 | Compound for encapsulation film and composition thereof, and film, organic light-emitting device and encapsulation method | AOX1, LOXL1, SEM1 | LSS 318/4885LTA4H 23/4885CHRNB2 4078/4885 |
| US-20030225058-A1 | Substituted azepino[4,5b]indoline derivatives | HTR5A, HTR1A, HTR4 | LSS 2026/4885LTA4H 1318/4885CHRNB2 200/4885 |
| US-11952450-B2 | Compound for encapsulation film and composition thereof, and film, organic light-emitting device and encapsulation method | TTPA, LOX, AOX1 | LSS 388/4885LTA4H 25/4885CHRNB2 3925/4885 |
| US-20030220321-A1 | Substituted azepino[4,5b]indole derivatives | HTR5A, HTR1A, HTR1E | LSS 1332/4885LTA4H 1066/4885CHRNB2 201/4885 |
| US-20020077318-A1 | Substituted azepino[4,5b] indoline derivatives | HTR5A, HTR1A, HTR4 | LSS 2026/4885LTA4H 1318/4885CHRNB2 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.