Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20660751 | 0.77 | ALDH1A1 (0.39) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| SCHEMBL23615638 | 0.77 | NPSR1 (0.38) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| SCHEMBL27593276 | 0.76 | PTGDR2 (0.34) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL2191688 | 0.73 | RAB9A (0.37) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| SCHEMBL12913757 | 0.73 | LMNA (0.35) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| SCHEMBL1029127 | 0.71 | KEAP1 (0.39) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| SCHEMBL14635737 | 0.70 | TRPM8 (0.52) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| SCHEMBL2471508 | 0.69 | CA1 (0.36) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| SCHEMBL21396202 | 0.69 | HRH4 (0.39) | KMT2AMEN1MAPTCYP1A2CYP3A4 | |
| SCHEMBL25322220 | 0.68 | MAPK1 (0.36) | KMT2AMEN1MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4785169-B2 | — | — | 2011-10-05 | — | — | JP | claimed |
| EP-1409440-A4 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM & HAAS (US) | 2005-09-14 | — | — | EP | claimed |
| US-20050065033-A1 | Method to inhibit ethylene responses in plants | JACOBSON RICHARD MARTIN (US) | 2005-03-24 | — | — | US | claimed |
| JP-2004532191-A | — | — | 2004-10-21 | — | — | JP | claimed |
| EP-1409440-A1 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM AND HAAS COMPANY (US) | 2004-04-21 | — | — | EP | claimed |
| WO-2002068367-A1 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM AND HAAS COMPANY (US) | 2002-09-06 | — | — | WO | claimed |
| US-20110190137-A1 | METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | JACOBSON RICHARD MARTIN | 2011-08-04 | — | — | US | disclosed |
| EP-1409440-A4 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM & HAAS (US) | 2005-09-14 | — | — | EP | disclosed |
| US-20050065033-A1 | Method to inhibit ethylene responses in plants | JACOBSON RICHARD MARTIN (US) | 2005-03-24 | — | — | US | disclosed |
| EP-1409440-A1 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM AND HAAS COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002068367-A1 | A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ROHM AND HAAS COMPANY (US) | 2002-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065033-A1 | Method to inhibit ethylene responses in plants | ERN1, CTH, CBS | KMT2A 3599/4885MEN1 3455/4885MAPT 4777/4885 |
| US-20110190137-A1 | METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS | ERN1, CTH, CBR3 | KMT2A 3641/4885MEN1 3399/4885MAPT 4775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.