Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 2/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.43 |
| ▸ | CPA1 | P15085 | 3/20 | 0.43 |
| ▸ | CPA2 | P48052 | 2/20 | 0.43 |
| ▸ | CPA4 | Q9UI42 | 2/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | CTSE | P14091 | 1/20 | 0.41 |
| ▸ | PGC | P20142 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286416 | 1.00 | LTA4H (0.47) | LTA4HANPEPERAP2ACE2CPA1 | |
| SCHEMBL10716075 | 0.84 | LTA4H (0.46) | LTA4HANPEPERAP2ACE2CPA1 | |
| SCHEMBL10716078 | 0.84 | LTA4H (0.46) | LTA4HANPEPERAP2ACE2CPA1 | |
| SCHEMBL7308139 | 0.84 | MMP1 (0.42) | LTA4HANPEPERAP2ACE2CPA1 | |
| SCHEMBL10715965 | 0.83 | ACE2 (0.53) | ACE2MMEACE | |
| Hydrochloric Acid SCHEMBL10718561 | 0.82 | ACE2 (0.48) | ANPEPERAP2ACE2CPA1CPA2 | |
| SCHEMBL7284748 | 0.81 | CPB2 (0.49) | CPB1 | |
| SCHEMBL7284754 | 0.81 | CPB2 (0.49) | CPB1 | |
| SCHEMBL10718428 | 0.80 | REN (0.44) | LTA4HANPEPERAP2ACE2CPA1 | |
| SCHEMBL10717475 | 0.80 | REN (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209897-A2 | Peptide enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | disclosed |