Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 5/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286409 | 0.84 | LTA4H (0.47) | MMP1MMP13ANPEPERAP2LTA4H | |
| SCHEMBL7286416 | 0.84 | LTA4H (0.47) | MMP1MMP13ANPEPERAP2LTA4H | |
| SCHEMBL7308131 | 0.75 | CTSD (0.45) | MMP1MMP13ANPEPERAP2LTA4H | |
| SCHEMBL10716075 | 0.72 | LTA4H (0.46) | MMP1ANPEPERAP2LTA4HREN | |
| SCHEMBL10716078 | 0.72 | LTA4H (0.46) | MMP1ANPEPERAP2LTA4HREN | |
| SCHEMBL7296156 | 0.71 | REN (0.49) | REN | |
| SCHEMBL10715965 | 0.71 | ACE2 (0.53) | MMEACEACE2 | |
| Hydrochloric Acid SCHEMBL10718561 | 0.71 | ACE2 (0.48) | MMP1ANPEPERAP2MMECPA1 | |
| SCHEMBL10718428 | 0.70 | REN (0.44) | ANPEPERAP2LTA4HRENMME | |
| Hydrochloric Acid SCHEMBL9848368 | 0.69 | CTSD (0.55) | RENBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209897-A2 | Peptide enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | claimed |