Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10718361 | 0.82 | REN (0.43) | RENMMEACEECE1LMNA | |
| SCHEMBL10718349 | 0.82 | CPB2 (0.46) | — | |
| SCHEMBL7286409 | 0.80 | LTA4H (0.47) | MMEACE2ACECPA1ANPEP | |
| SCHEMBL10715965 | 0.80 | ACE2 (0.53) | MMEACE2ACEECE1 | |
| SCHEMBL7286416 | 0.80 | LTA4H (0.47) | MMEACE2ACECPA1ANPEP | |
| SCHEMBL10717475 | 0.75 | REN (0.47) | RENLMNA | |
| SCHEMBL10717422 | 0.74 | MMP1 (0.40) | ANPEPERAP2 | |
| SCHEMBL25453220 | 0.71 | MMP8 (0.56) | HPRT1ACEANPEPLMNA | |
| SCHEMBL21578811 | 0.71 | MMP8 (0.56) | HPRT1ACEANPEPLMNA | |
| SCHEMBL7308139 | 0.70 | MMP1 (0.42) | RENMMEACE2ACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | claimed |
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | disclosed |