Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 15/20 | 0.44 |
| ▸ | MMP3 | P08254 | 7/20 | 0.44 |
| ▸ | MMP1 | P03956 | 4/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | MMP14 | P50281 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287009 | 1.00 | MMP2 (0.44) | MMP2MMP3MMP1MMP7MMP9 | |
| SCHEMBL7287864 | 0.97 | MMP3 (0.44) | MMP2MMP3MMP1MMP7MMP9 | |
| SCHEMBL7287870 | 0.97 | MMP3 (0.44) | MMP2MMP3MMP1MMP7MMP9 | |
| SCHEMBL7293298 | 0.94 | MMP1 (0.39) | MMP3MMP1 | |
| SCHEMBL7293294 | 0.94 | MMP1 (0.39) | MMP3MMP1 | |
| SCHEMBL7292514 | 0.90 | CTSL (0.40) | MMP1 | |
| SCHEMBL7292510 | 0.90 | CTSL (0.40) | MMP1 | |
| SCHEMBL7302891 | 0.86 | GLS (0.39) | — | |
| SCHEMBL7302898 | 0.86 | GLS (0.39) | — | |
| SCHEMBL10826321 | 0.85 | MMP1 (0.49) | MMP2MMP3MMP1MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264106-B1 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4851387-A | RENIN INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0264106-A2 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-04-20 | — | — | EP | disclosed |