Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | FCER2 | P06734 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 7/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.39 |
| ▸ | IL1RN | P18510 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 3/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293298 | 1.00 | MMP1 (0.39) | MMP1FCER2ERAP2LNPEPERAP1 | |
| SCHEMBL7287009 | 0.94 | MMP2 (0.44) | MMP1MMP3 | |
| SCHEMBL7287005 | 0.94 | MMP2 (0.44) | MMP1MMP3 | |
| SCHEMBL7287864 | 0.93 | MMP3 (0.44) | MMP1MMP3 | |
| SCHEMBL7287870 | 0.93 | MMP3 (0.44) | MMP1MMP3 | |
| SCHEMBL7292510 | 0.92 | CTSL (0.40) | MMP1FCER2CTSC | |
| SCHEMBL7292514 | 0.92 | CTSL (0.40) | MMP1FCER2CTSC | |
| SCHEMBL7302898 | 0.85 | GLS (0.39) | CTSC | |
| SCHEMBL7302891 | 0.85 | GLS (0.39) | CTSC | |
| SCHEMBL9012384 | 0.84 | CTSC (0.54) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264106-B1 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4851387-A | RENIN INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0264106-A2 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-04-20 | — | — | EP | disclosed |