SCHEMBL729002

SCHEMBL729002

CCc1cc(Cc2ccc(OC#N)c(CC)c2)ccc1OC#N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.41
GAA P10253 1/20 0.38
AKT1 P31749 1/20 0.36
CFD P00746 1/20 0.36
CYP2A6 P11509 1/20 0.34
ALDH1A1 P00352 2/20 0.34
DHFR P00374 1/20 0.33
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33
TUBB4B P68371 1/20 0.33
TUBB3 Q13509 1/20 0.33
TUBB2A Q13885 1/20 0.33
TUBB8 Q3ZCM7 1/20 0.33
TUBA3E Q6PEY2 1/20 0.33
TUBA1A Q71U36 1/20 0.33
TUBA1C Q9BQE3 1/20 0.33
TUBB6 Q9BUF5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30423749 1.00 CA2 (0.41) CA2GAAAKT1CFDCYP2A6
SCHEMBL11854282 0.91 AKT1 (0.40) AKT1CYP2A6ALDH1A1HSD17B10
SCHEMBL27516451 0.80 L3MBTL1 (0.40) CA2GAAALDH1A1SLC6A4HSD17B10
SCHEMBL8993094 0.78 GABRA1 (0.41) CA2ALDH1A1
SCHEMBL727075 0.78 ESR1 (0.44) CA2GAACFDALDH1A1TUBB4A
SCHEMBL30259656 0.78 ESR1 (0.44) CA2GAACFDALDH1A1TUBB4A
SCHEMBL20286678 0.77 CA2 (0.63) CA2GAAALDH1A1TUBB4ATUBB
SCHEMBL8518746 0.76 CYP2A6 (0.39) AKT1CYP2A6ALDH1A1HSD17B10KMT2A
SCHEMBL23597026 0.76 DHFR (0.36) DHFR
SCHEMBL829807 0.74 CYP3A4 (0.44) CA2GAAALDH1A1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8575239-B2 Curing composition and cured product prepared by using the same LG CHEM, LTD. (KR) 2013-11-05 US claimed
EP-2231781-B1 CURING COMPOSITION AND CURED PRODUCT PREPARED BY USING THE SAME LG CHEMICAL LTD (KR) 2012-09-26 EP claimed
JP-2011525198-A 2011-09-15 JP claimed
US-20100286302-A1 CURING COMPOSITION AND CURED PRODUCT PREPARED BY USING THE SAME SHANJIN OPTOELECTRONICS (SUZHOU) CO., LTD. (CN) 2010-11-11 US claimed
EP-2231781-A2 CURING COMPOSITION AND CURED PRODUCT PREPARED BY USING THE SAME LG Chem, Ltd. (KR) 2010-09-29 EP claimed
WO-2009084861-A2 CURING COMPOSITION AND CURED PRODUCT PREPARED BY USING THE SAME LG CHEM, LTD. (KR) 2009-07-09 WO claimed
US-12565608-B2 Thermally conductive resin composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-03-03 US disclosed
US-20250382414-A1 RECYCLABLE AND MALLEABLE THERMOSETS ENABLED BY ACTIVATING DORMANT DYNAMIC LINKAGES UNIV COLORADO REGENTS (US) 2025-12-18 US disclosed
CN-119998359-A Recoverable and extensible thermoset achieved by activation of dormant dynamic bonds 科罗拉多大学董事会, 法人团体 2025-05-13 CN disclosed
US-20250001725-A1 GLASS CLOTH COMPOSITE MATERIAL SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-01-02 US disclosed
US-20240351981-A1 NOVEL BISMALEIMIDE COMPOUNDS HAVING IMPROVED SOLUBILITY AND THEIR USE IN CURABLE COMPOSITIONS EVONIK OPERATIONS GMBH (DE) 2024-10-24 US disclosed
CN-116157915-B Thermosetting resin composition and semiconductor device 信越化学工业株式会社 2024-09-24 CN disclosed
EP-4380922-A1 NOVEL BISMALEIMIDE COMPOUNDS HAVING IMPROVED SOLUBILITY AND THEIR USE IN CURABLE COMPOSITIONS Evonik Operations GmbH (DE) 2024-06-12 EP disclosed
EP-1208159-A1 CYANATE ESTER BASED THERMOSET COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2002-05-29 EP disclosed
US-20010016616-A1 Cyanate ester based thermoset compositions CERBERUS BUSINESS FINANCE, LLC, AS COLLATERAL AGENT (FIRST LIEN) 2001-08-23 US disclosed
US-6245841-B1 BLEND CONTAINING FLAME RETARDER AND CURING AGENT GENERAL ELECTRIC COMPANY 2001-06-12 US disclosed
US-6194495-B1 CURBLE COMPOSITION WITH ARYLOXYTRIAZINE GENERAL ELECTRIC COMPANY 2001-02-27 US disclosed
WO-2001009247-A1 CYANATE ESTER BASED THERMOSET COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2001-02-08 WO disclosed
US-6162876-A Cyanate ester based thermoset compositions GENERAL ELECTRIC COMPANY (US) 2000-12-19 US disclosed
EP-0945477-A1 Cyanate ester based thermoset compositions GENERAL ELECTRIC COMPANY (US) 1999-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565608-B2 Thermally conductive resin composition ITGAM, RAE1, FCGR1A CA2 1047/4885GAA 4416/4885AKT1 1869/4885
US-20250382414-A1 RECYCLABLE AND MALLEABLE THERMOSETS ENABLED BY ACTIVATING DORMANT DYNAMIC LINKAGES CDK4, TRIB2, KDM4B CA2 3822/4885GAA 4366/4885AKT1 3622/4885
US-20240351981-A1 NOVEL BISMALEIMIDE COMPOUNDS HAVING IMPROVED SOLUBILITY AND THEIR USE IN CURABLE COMPOSITIONS PBRM1, SMCHD1, SMARCE1 CA2 1507/4885GAA 2325/4885AKT1 3359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.