Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7201014 | 0.88 | SMN1; SMN2 (0.41) | AKR1C3AKR1C1MMP1MMP13SMN1; SMN2 | |
| SCHEMBL7204213 | 0.88 | MMP13 (0.52) | AKR1C3AKR1C1MMP1MMP13SCN9A | |
| SCHEMBL7205673 | 0.88 | MMP1 (0.39) | MMP1MMP13DPP4DPP7KDM2B | |
| SCHEMBL7204066 | 0.86 | ALDH1A1 (0.38) | MMP1MMP13CNR1ADAMTS4ALDH1A1 | |
| SCHEMBL7204539 | 0.86 | MMP1 (0.40) | MMP1MMP13DPP4DPP7KDM2B | |
| SCHEMBL7199700 | 0.83 | MMP1 (0.42) | MMP1MMP13ADAMTS4SMN1; SMN2ALDH1A1 | |
| SCHEMBL7290273 | 0.83 | MGLL (0.41) | AKR1C3AKR1C1MMP1MMP13KDM2B | |
| SCHEMBL7201540 | 0.82 | ADAMTS4 (0.39) | MMP1MMP13DPP4ADAMTS4 | |
| SCHEMBL7300738 | 0.82 | MMP13 (0.48) | MMP1MMP13RAB9ANPC1ALDH1A1 | |
| SCHEMBL7202625 | 0.82 | CCR6 (0.39) | MMP1MMP13DPP4DPP7KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1138680-A1 | Gem substituted sulfonyl hydroxamic acids as MMP inhibitors | Pfizer Products Inc. (US) | 2001-10-04 | — | — | EP | disclosed |