Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.34 |
| ▸ | MMP9 | P14780 | 4/20 | 0.34 |
| ▸ | MMP12 | P39900 | 4/20 | 0.34 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285845 | 0.70 | MMP1 (0.35) | MMP1MMP9MMP12MMP2GPR84 | |
| SCHEMBL7294301 | 0.70 | GPR84 (0.36) | MMP1MMP9MMP12MMP2GPR84 | |
| SCHEMBL7286062 | 0.67 | MAPK14 (0.30) | — | |
| SCHEMBL7293169 | 0.64 | MMP1 (0.35) | MMP1MMP9MMP12GPR84 | |
| SCHEMBL7285267 | 0.60 | PKM (0.47) | MMP1MMP9MMP12MMP2NOTUM | |
| SCHEMBL20334042 | 0.58 | ABCB11 (0.35) | — | |
| SCHEMBL7286302 | 0.57 | NOTUM (0.36) | MMP1MMP9MMP12MMP2GPR84 | |
| SCHEMBL10313323 | 0.57 | GPR84 (0.41) | MMP1MMP9MMP12MMP2GPR84 | |
| SCHEMBL7296669 | 0.57 | GPR84 (0.44) | MMP1MMP9MMP12GPR84NOTUM | |
| SCHEMBL31453175 | 0.56 | MMP1 (0.49) | MMP1MMP9MMP12MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863938-A | Pyridine derivatives and their use as nootropic agents | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | claimed |
| EP-0239533-B1 | PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-16 | — | — | EP | disclosed |
| US-4863938-A | Pyridine derivatives and their use as nootropic agents | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |