SCHEMBL729586

SCHEMBL729586

CN(C)c1ccc(C(=O)O)c(O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.57
MAOB P27338 3/20 0.57
ALDH1A1 P00352 7/20 0.55
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
TSHR P16473 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
MAPT P10636 3/20 0.53
HPGD P15428 3/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
NPC1 O15118 1/20 0.53
TP53 P04637 1/20 0.53
KDM4E B2RXH2 5/20 0.52
GAA P10253 2/20 0.52
CYP3A4 P08684 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22938991 0.88 MEN1 (0.58) MAOAMAOBALDH1A1CA12CA1
SCHEMBL22939649 0.86 ALDH1A1 (0.64) MAOAMAOBALDH1A1TSHRMAPT
SCHEMBL6205557 0.85 KMT2A (0.72) MAOAMAOBALDH1A1TSHRMAPT
SCHEMBL29570529 0.85 KMT2A (0.72) MAOAMAOBALDH1A1TSHRMAPT
SCHEMBL144363 0.84 MAOB (0.57) MAOAMAOBALDH1A1TSHRMAPT
SCHEMBL130505 0.84 CSNK2A1 (0.57) ALDH1A1CA12CA1CA2CA7
SCHEMBL30728533 0.84 MAOB (0.57) MAOAMAOBALDH1A1TSHRMAPT
SCHEMBL22939013 0.84 ALDH1A1 (0.61) MAOAMAOBALDH1A1CA12CA1
SCHEMBL8646935 0.83 SLC16A3 (0.51) MAOAMAOBALDH1A1TSHRMAPT
SCHEMBL22939007 0.83 MEN1 (0.60) MAOAMAOBALDH1A1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528921-A Rhodamine-coumarin based fluorescent probe, fluorescent sensitive film, and preparation methods and applications thereof 兰州大学 2025-02-28 CN claimed
US-20180064667-A1 METHODS OF TREATING LACTOSE INTOLERANCE NOGRA PHARMA LTD (IE) 2018-03-08 US claimed
US-20150087678-A1 METHODS OF TREATING LACTOSE INTOLERANCE NOGRA PHARMA LIMITED (IE) 2015-03-26 US claimed
EP-2844242-A1 METHODS OF TREATING LACTOSE INTOLERANCE Nogra Pharma Limited (IE) 2015-03-11 EP claimed
CN-104284655-A Methods of treating lactose intolerance NOGRA PHARMA LTD 2015-01-14 CN claimed
WO-2013156413-A1 METHODS OF TREATING LACTOSE INTOLERANCE NOGRA PHARMA LIMITED (IE) 2013-10-24 WO claimed
US-20110152225-A1 PPAR-Gamma Agonists for the Induction of Cationic Antimicrobial Peptide Expression as Immunoprotective Stimulants NOGRA PHARMA LIMITED (IE) 2011-06-23 US claimed
EP-2131829-A1 PPAR-GAMMA AGONISTS FOR THE INDUCTION OF CATIONIC ANTIMICROBIAL PEPTIDE EXPRESSION AS IMMUNOPROTECTIVE STIMULANTS Giuliani International Limited (IE) 2009-12-16 EP claimed
US-20090118357-A1 Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field GIULIANI INTERNATIONAL LIMITED (IE) 2009-05-07 US claimed
WO-2008104557-A1 PPAR-GAMMA AGONISTS FOR THE INDUCTION OF CATIONIC ANTIMICROBIAL PEPTIDE EXPRESSION AS IMMUNOPROTECTIVE STIMULANTS GIULIANI INTERNATIONAL LIMITED (IE) 2008-09-04 WO claimed
US-12291494-B2 Methods of treating fibrosis NOGRA PHARMA LIMITED (IE) 2025-05-06 US disclosed
CN-119528921-A Rhodamine-coumarin based fluorescent probe, fluorescent sensitive film, and preparation methods and applications thereof 兰州大学 2025-02-28 CN disclosed
US-20240279157-A1 METHODS OF TREATING FIBROSIS NOGRA PHARMA LIMITED (IE) 2024-08-22 US disclosed
US-11753365-B2 Methods of treating fibrosis NOGRA PHARMA LIMITED (IE) 2023-09-12 US disclosed
CN-116602950-A Methods of treating fibrosis 诺格拉制药有限公司 2023-08-18 CN disclosed
US-5055374-A Positive working resist NIPPON PAINT CO., LTD. (JP) 1991-10-08 US disclosed
US-4999274-A Obtained by Reacting a Polyepoxide Compound, an Aromatic or Heterocyclic Carboxylic Acid Bearing a Phenolic Hydroxyl Group and a 1,2-Quinondiazido Sulfonyl Halide; Lithographic Plates, Photoresists NIPPON PAINT CO., LTD. (JP) 1991-03-12 US disclosed
EP-0354018-A2 An electrodeposition coating composition and image-forming method using the same NIPPON PAINT CO., LTD. (JP) 1990-02-07 EP disclosed
EP-0302941-A1 POSITIVE PHOTOSENSITIVE RESIN COMPOSITION AND PROCESS FOR ITS PRODUCTION NIPPON PAINT CO., LTD. (JP) 1989-02-15 EP disclosed
US-4247597-A Electroscopic carrier particles having a carboxylic acid surface treatment PITNEY BOWES, INC. (US) 1981-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090118357-A1 Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field EGFR, ERBB3, FGFR3 MAOA 3924/4885MAOB 3247/4885ALDH1A1 2287/4885
US-11753365-B2 Methods of treating fibrosis MMP1, MMP8, FABP2 MAOA 1738/4885MAOB 950/4885ALDH1A1 664/4885
US-20240279157-A1 METHODS OF TREATING FIBROSIS MMP1, MMP8, FABP2 MAOA 1738/4885MAOB 950/4885ALDH1A1 664/4885
US-20150087678-A1 METHODS OF TREATING LACTOSE INTOLERANCE LCT, LPL, PPARG MAOA 3500/4885MAOB 2825/4885ALDH1A1 530/4885
US-12291494-B2 Methods of treating fibrosis MMP1, MMP8, FABP2 MAOA 1738/4885MAOB 950/4885ALDH1A1 664/4885
US-20180064667-A1 METHODS OF TREATING LACTOSE INTOLERANCE LCT, LPL, PPARG MAOA 3500/4885MAOB 2825/4885ALDH1A1 530/4885
US-20110152225-A1 PPAR-Gamma Agonists for the Induction of Cationic Antimicrobial Peptide Expression as Immunoprotective Stimulants PPARG, FABP2, PPARD MAOA 3577/4885MAOB 3944/4885ALDH1A1 983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.