Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301298 | 0.91 | KMT2A (0.48) | RENLDHAALDH1A1KMT2AITGA4 | |
| SCHEMBL9833395 | 0.85 | GAA (0.46) | LDHAALDH1A1KMT2AGAARAB9A | |
| SCHEMBL7292751 | 0.81 | KMT2A (0.55) | ALDH1A1KMT2AMEN1LMNAGAA | |
| SCHEMBL9832460 | 0.81 | LDHA (0.50) | LDHAALDH1A1KMT2AGAARAB9A | |
| SCHEMBL7430899 | 0.77 | ALDH1A1 (0.44) | RENLDHAALDH1A1KMT2AGAA | |
| SCHEMBL7306601 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1GAARAB9A | |
| SCHEMBL10534728 | 0.75 | FPR2 (0.53) | LDHAALDH1A1KMT2AITGA4ITGB7 | |
| SCHEMBL7333858 | 0.74 | L3MBTL1 (0.45) | ALDH1A1KMT2ALMNAGAAITGA4 | |
| SCHEMBL16879018 | 0.74 | LDHA (0.54) | LDHAALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL16879017 | 0.74 | LDHA (0.54) | LDHAALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341602-A2 | Renin-inhibiting functionalized peptidyl aminodiols and - triols | ABBOTT LABORATORIES (US) | 1989-11-15 | — | — | EP | disclosed |