Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | IL2 | P60568 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296180 | 0.91 | REN (0.43) | KMT2AFPR2ITGA4ITGB7LDHA | |
| SCHEMBL10534728 | 0.85 | FPR2 (0.53) | KMT2AFPR2CA2ITGA4ITGB7 | |
| SCHEMBL7333858 | 0.83 | L3MBTL1 (0.45) | KMT2AFPR2ITGA4ITGB7ALDH1A1 | |
| SCHEMBL7301518 | 0.82 | KMT2A (0.65) | KMT2AFPR2CA2ITGA4ITGB7 | |
| SCHEMBL9834187 | 0.81 | FPR2 (0.59) | KMT2AFPR2CA2ITGA4ITGB7 | |
| SCHEMBL7431334 | 0.77 | KMT2A (0.50) | KMT2AFPR2CA2ITGA4ITGB7 | |
| SCHEMBL7305859 | 0.76 | KMT2A (0.52) | KMT2AFPR2ITGA4ITGB7ALDH1A1 | |
| SCHEMBL9833395 | 0.75 | GAA (0.46) | KMT2AFPR2ITGA4ITGB7LDHA | |
| SCHEMBL7292751 | 0.74 | KMT2A (0.55) | KMT2AFPR2ALDH1A1 | |
| SCHEMBL6438360 | 0.74 | ITGB3 (0.64) | KMT2AFPR2CA2LDHAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989010751-A1 | FUNCTIONALIZED PEPTIDYL AMINODIOLS AND -TRIOLS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |
| EP-0341602-A2 | Renin-inhibiting functionalized peptidyl aminodiols and - triols | ABBOTT LABORATORIES (US) | 1989-11-15 | — | — | EP | disclosed |