Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305859 | 0.92 | KMT2A (0.52) | ALDH1A1KDM4EHIF1AKMT2AMEN1 | |
| SCHEMBL7292751 | 0.85 | KMT2A (0.55) | ALDH1A1RAB9AGAAKMT2AMEN1 | |
| SCHEMBL7274220 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KDM4EHIF1ARAB9AKMT2A | |
| SCHEMBL27303428 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KDM4EHIF1ARAB9AKMT2A | |
| SCHEMBL7274173 | 0.82 | KMT2A (0.51) | ALDH1A1KDM4EHIF1ARAB9AKMT2A | |
| SCHEMBL9833395 | 0.81 | GAA (0.46) | ALDH1A1HDAC6HDAC1RAB9AGAA | |
| SCHEMBL7301518 | 0.78 | KMT2A (0.65) | ALDH1A1KMT2A | |
| SCHEMBL9832460 | 0.77 | LDHA (0.50) | ALDH1A1HDAC6HDAC1RAB9AGAA | |
| SCHEMBL7296180 | 0.76 | REN (0.43) | ALDH1A1RAB9AGAAKMT2AMEN1 | |
| SCHEMBL7430899 | 0.73 | ALDH1A1 (0.44) | ALDH1A1RAB9AGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410260-A2 | Peptidyl aminodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-01-30 | — | — | EP | disclosed |