Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.40 |
| ▸ | C1S | P09871 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | AGXT | P21549 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304178 | 0.99 | TERT (0.41) | TERTC1SDHFRALDH1A1GAA | |
| SCHEMBL1924454 | 0.76 | ALDH1A1 (0.53) | ALDH1A1GAAHTTSMN1; SMN2KCNH2 | |
| SCHEMBL7167684 | 0.71 | NOS2 (0.53) | ALDH1A1HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL255378 | 0.70 | ALDH1A1 (0.52) | C1SALDH1A1GAAHTTNPC1 | |
| SCHEMBL30167608 | 0.70 | ALDH1A1 (0.52) | C1SALDH1A1GAAHTTNPC1 | |
| SCHEMBL3159432 | 0.69 | SMN1; SMN2 (0.50) | C1SALDH1A1GAAHTTNPC1 | |
| SCHEMBL20985347 | 0.68 | BRD4 (0.40) | ALDH1A1KCNH2 | |
| SCHEMBL24529 | 0.68 | TP53 (0.55) | TERTALDH1A1SMN1; SMN2 | |
| SCHEMBL30407553 | 0.67 | BPTF (0.51) | C1SALDH1A1GAAHTTNPC1 | |
| SCHEMBL14247826 | 0.67 | DHFR (0.46) | DHFRHTTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520200-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1998-02-18 | — | — | EP | disclosed |
| EP-0520200-A2 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1992-12-30 | — | — | EP | disclosed |