Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.43 |
| ▸ | CTSL | P07711 | 7/20 | 0.43 |
| ▸ | CTSS | P25774 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.39 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304422 | 0.81 | CTSL (0.50) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7306148 | 0.80 | CTSL (0.51) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7316936 | 0.75 | CTSL (0.49) | CTSKCTSLCTSSCTSBCACNA1B | |
| SCHEMBL7306604 | 0.70 | MAPT (0.46) | CTSKCTSLCTSSALDH1A1CTSB | |
| SCHEMBL7316235 | 0.68 | FNTA (0.39) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7312048 | 0.68 | FNTA (0.39) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7306274 | 0.68 | EBP (0.39) | CTSKCTSLCTSSALDH1A1HPGD | |
| SCHEMBL7316501 | 0.68 | CTSL (0.44) | CTSKCTSLCTSSCTSBCACNA1B | |
| SCHEMBL7311694 | 0.68 | CTSL (0.44) | CTSKCTSLCTSSCTSBCACNA1B | |
| SCHEMBL7306462 | 0.68 | KIF11 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |