Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 3/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317031 | 0.77 | MMP9 (0.46) | LMNAALDH1A1HPGDS | |
| SCHEMBL7303559 | 0.77 | GAA (0.44) | LMNATSHRGAAALDH1A1KMT2A | |
| SCHEMBL7307216 | 0.75 | CTSC (0.47) | LMNATSHRNPSR1METAP2KMT2A | |
| SCHEMBL11442593 | 0.73 | ALDH1A1 (0.49) | LMNANPSR1BCAT2MAPTALDH1A1 | |
| SCHEMBL7316408 | 0.71 | LMNA (0.50) | LMNATSHREPHX1NPSR1BCAT2 | |
| SCHEMBL7314848 | 0.70 | MEN1 (0.52) | LMNATSHREPHX1ALDH1A1KMT2A | |
| SCHEMBL27488761 | 0.70 | MEN1 (0.52) | LMNATSHREPHX1ALDH1A1KMT2A | |
| SCHEMBL7316181 | 0.70 | MEN1 (0.52) | LMNATSHREPHX1ALDH1A1KMT2A | |
| SCHEMBL4956720 | 0.70 | ACE (0.49) | — | |
| SCHEMBL17161710 | 0.69 | MEN1 (0.53) | MAPTALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |