Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.45 |
| ▸ | F10 | P00742 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 9/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307345 | 0.76 | ITGB3 (0.47) | ITGB3ITGA2BF10SIGMAR1 | |
| SCHEMBL7314436 | 0.72 | ITGB3 (0.48) | ITGB3ITGA2BF10ALDH1A1PLA2G2A | |
| SCHEMBL8858130 | 0.71 | ITGB3 (0.45) | ITGB3ITGA2BF10ALDH1A1PLA2G2A | |
| SCHEMBL8892671 | 0.70 | ITGB3 (0.49) | ITGB3ITGA2BF10ALDH1A1PLA2G2A | |
| SCHEMBL7460284 | 0.69 | ITGB3 (0.46) | ITGB3ITGA2BF10ALDH1A1PLA2G2A | |
| SCHEMBL6606264 | 0.69 | ITGB3 (0.58) | ITGB3ITGA2BF10ALDH1A1 | |
| SCHEMBL8893341 | 0.69 | ITGB3 (0.56) | ITGB3ITGA2BF10ALDH1A1PLA2G2A | |
| SCHEMBL7307035 | 0.68 | OPRM1 (0.33) | — | |
| SCHEMBL7461633 | 0.68 | ITGB3 (0.51) | ITGB3ITGA2BF10ALDH1A1PLA2G2A | |
| SCHEMBL8858128 | 0.67 | ITGB3 (0.46) | ITGB3ITGA2BF10ALDH1A1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |