Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 10/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 10/20 | 0.48 |
| ▸ | PRKAB1 | Q9Y478 | 10/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 9/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 8/20 | 0.48 |
| ▸ | PRKAG3 | Q9UGI9 | 8/20 | 0.48 |
| ▸ | PRKAG2 | Q9UGJ0 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966664 | 0.95 | PRKAG1 (0.47) | PRKAG1PRKAA1PRKAB1PRKAA2PRKAB2 | |
| SCHEMBL25680334 | 0.89 | TSHR (0.48) | KMT2AMEN1SRD5A2HNF4ATP53 | |
| SCHEMBL13374166 | 0.85 | CYP2C9 (0.49) | PRKAG1PRKAA1PRKAB1PRKAA2PRKAB2 | |
| SCHEMBL7189606 | 0.82 | PRKAG1 (0.43) | PRKAG1PRKAA1PRKAB1PRKAA2PRKAB2 | |
| SCHEMBL14300774 | 0.81 | KCNH2 (0.41) | PRKAG1PRKAA1PRKAB1PRKAA2PRKAB2 | |
| SCHEMBL18394292 | 0.79 | KMT2A (0.54) | PRKAG1PRKAA1PRKAB1PRKAA2PRKAB2 | |
| Bicarbonate SCHEMBL27428524 | 0.78 | SLC18A3 (0.47) | PRKAG1PRKAA1PRKAB1PRKAA2PRKAB2 | |
| SCHEMBL18215382 | 0.77 | TSHR (0.54) | PRKAG1PRKAA1PRKAB1PRKAA2PRKAB2 | |
| SCHEMBL28416 | 0.77 | TSHR (0.54) | PRKAG1PRKAA1PRKAB1PRKAA2PRKAB2 | |
| SCHEMBL4444258 | 0.77 | TSHR (0.54) | SRD5A2TP53TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130190502-A1 | ACYLATION REACTION OF HYDROXYL GROUP | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-07-25 | — | — | US | disclosed |
| US-8431709-B2 | Acylation reaction of hydroxyl group | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-04-30 | — | — | US | disclosed |
| EP-2179007-B1 | ALKALOID MONOMERS, LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | DU PONT (US) | 2012-10-17 | — | — | EP | disclosed |
| US-8137582-B2 | Alkaloid monomers, liquid crystal compositions and polymer networks derived therefrom | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-20 | — | — | US | disclosed |
| US-20110193019-A1 | ALKALOID MONOMERS, LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-08-11 | — | — | US | disclosed |
| US-20100249422-A1 | ACYLATION REACTION OF HYDROXYL GROUP | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2196451-A1 | ACYLATION REACTION OF HYDROXYL GROUP | Takasago International Corporation (JP) | 2010-06-16 | — | — | EP | disclosed |
| EP-2179007-A1 | ALKALOID MONOMERS, LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | E. I. du Pont de Nemours and Company (US) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009023762-A1 | ALKALOID MONOMERS, LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-02-19 | — | — | WO | disclosed |
| EP-1976511-A2 | FLUORINATED ARYLAMIDE DERIVATIVES | Merck & Co., Inc. (US) | 2008-10-08 | — | — | EP | disclosed |
| EP-1973405-A2 | HYDROXYALKYLARYLAMIDE DERIVATIVES | Merck & Co., Inc. (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007087130-A2 | HYDROXYALKYLARYLAMIDE DERIVATIVES | MERCK & CO., INC. (US) | 2007-08-02 | — | — | WO | disclosed |
| WO-2007087129-A2 | FLUORINATED ARYLAMIDE DERIVATIVES | MERCK & CO., INC. (US) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110193019-A1 | ALKALOID MONOMERS, LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | BHMT, BHMT2, NOTUM | PRKAG1 4337/4885PRKAA1 4032/4885PRKAB1 4496/4885 |
| US-20130190502-A1 | ACYLATION REACTION OF HYDROXYL GROUP | ADH5, ADH1A, ACADM | PRKAG1 2341/4885PRKAA1 685/4885PRKAB1 2760/4885 |
| US-20100249422-A1 | ACYLATION REACTION OF HYDROXYL GROUP | ADH5, ADH1A, ACADM | PRKAG1 2341/4885PRKAA1 685/4885PRKAB1 2760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.