Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313885 | 0.97 | GPR119 (0.38) | GPR119MAPK1L3MBTL1FAAH | |
| SCHEMBL7314189 | 0.94 | GPR119 (0.33) | GPR119FAAHRORC | |
| SCHEMBL7313917 | 0.90 | SIGMAR1 (0.34) | MAPK1L3MBTL1 | |
| SCHEMBL7310460 | 0.88 | SIGMAR1 (0.34) | MAPK1L3MBTL1 | |
| SCHEMBL7313718 | 0.86 | SIGMAR1 (0.31) | MAPK1L3MBTL1 | |
| SCHEMBL7235475 | 0.83 | USP30 (0.32) | GPR119 | |
| SCHEMBL7306785 | 0.82 | GPR119 (0.33) | GPR119FAAH | |
| SCHEMBL7307904 | 0.81 | GPR119 (0.34) | GPR119 | |
| SCHEMBL7306960 | 0.81 | GPR119 (0.33) | GPR119FAAH | |
| SCHEMBL7310946 | 0.81 | GPR119 (0.33) | GPR119FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |