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SCHEMBL7313885

SCHEMBL7313885

CC(C)(C)OC(=O)NC(=N)N1CCC(CCCN2CC(COS(C)(=O)=O)OC2=O)CC1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 16/20 0.38
▸ FAAH O00519 1/20 0.33
▸ MAPK1 P28482 1/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ SCN9A Q15858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7307684 0.97 GPR119 (0.39) GPR119FAAHMAPK1L3MBTL1
SCHEMBL7314189 0.95 GPR119 (0.33) GPR119FAAHSCN9A
SCHEMBL7310460 0.89 SIGMAR1 (0.34) MAPK1L3MBTL1
SCHEMBL7313917 0.89 SIGMAR1 (0.34) MAPK1L3MBTL1
SCHEMBL7313718 0.87 SIGMAR1 (0.31) MAPK1L3MBTL1
SCHEMBL7235475 0.83 USP30 (0.32) GPR119
SCHEMBL7306190 0.82 GPR119 (0.32) GPR119FAAH
SCHEMBL7316507 0.81 FAAH (0.33) GPR119FAAH
SCHEMBL7306733 0.81 GPR119 (0.33) GPR119FAAH
SCHEMBL7313311 0.80 FAAH (0.33) GPR119FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5776937-A Adhesion receptor antagonists MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1998-07-07 — — US disclosed
EP-0727425-A1 Adhesion receptor antagonists MERCK PATENT GmbH (DE) 1996-08-21 — — EP disclosed
EP-0711770-A1 Antagonists of adhesion receptors MERCK PATENT GmbH (DE) 1996-05-15 — — EP disclosed