Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.46 |
| ▸ | PTGIR | P43119 | 4/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1689633 | 1.00 | CASR (0.49) | CASRHTR1ANISCHPTGIRSIRT2 | |
| SCHEMBL6102026 | 1.00 | CASR (0.49) | CASRHTR1ANISCHPTGIRSIRT2 | |
| SCHEMBL17150936 | 0.84 | CASR (0.50) | CASRHTR1ANISCH | |
| SCHEMBL2685298 | 0.83 | CASR (0.49) | CASRHTR1ANISCHPTGIRSIRT2 | |
| SCHEMBL7817626 | 0.82 | NISCH (0.48) | NISCHPTGIR | |
| SCHEMBL6098334 | 0.82 | NISCH (0.48) | NISCHPTGIR | |
| SCHEMBL5645322 | 0.81 | NISCH (0.50) | CASRNISCHPTGIR | |
| SCHEMBL6100304 | 0.81 | NISCH (0.49) | HTR1ANISCHPTGIR | |
| SCHEMBL31378741 | 0.81 | RORC (0.39) | CASRNISCH | |
| SCHEMBL6971604 | 0.81 | NISCH (0.51) | HTR1ANISCHSIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177513-B1 | PHENYLACETIC ACID COMPOUND | ONO PHARMACEUTICAL CO (JP) | 2015-07-01 | — | — | EP | disclosed |
| US-20140357630-A1 | Phenylacetic Acid Compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-12-04 | — | — | US | disclosed |
| US-20140357630-A1 | Phenylacetic Acid Compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-12-04 | — | — | US | disclosed |
| US-8809524-B2 | Phenylacetic acid compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-08-19 | — | — | US | disclosed |
| US-8809524-B2 | Phenylacetic acid compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-08-19 | — | — | US | disclosed |
| US-20130225808-A1 | PHENYLACETIC ACID COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-08-29 | — | — | US | disclosed |
| US-20130225808-A1 | PHENYLACETIC ACID COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-08-29 | — | — | US | disclosed |
| US-8476266-B2 | Phenylacetic acid compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-07-02 | — | — | US | disclosed |
| US-8476266-B2 | Phenylacetic acid compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-07-02 | — | — | US | disclosed |
| US-20130028887-A1 | PHENYLACETIC ACID COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-01-31 | — | — | US | disclosed |
| US-7135495-B2 | Indole derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-11-14 | — | — | US | disclosed |
| US-20060194864-A1 | Indole derivatives | ONO PHARMACEUTICAL CO., LTD. | 2006-08-31 | — | — | US | disclosed |
| US-20060089353-A1 | Indole derivative compounds and drugs containing the compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-04-27 | — | — | US | disclosed |
| EP-1600440-A1 | INDOLE DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-11-30 | — | — | EP | disclosed |
| US-20050222216-A1 | Carboxyoic acid compounds and drugs containing the compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-10-06 | — | — | US | disclosed |
| US-20050004097-A1 | Indole derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| US-20050004096-A1 | Indole derivatives, process for producing the same and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-1486491-A1 | CARBOXYOIC ACID COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-12-15 | — | — | EP | disclosed |
| EP-1424325-A1 | INDOLE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-06-02 | — | — | EP | disclosed |
| EP-1424335-A1 | INDOLE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194864-A1 | Indole derivatives | IDO1, IDO2, PTGIR | CASR 611/4885HTR1A 85/4885NISCH 2195/4885 |
| US-20050004097-A1 | Indole derivatives | IDO1, IDO2, PTGIR | CASR 611/4885HTR1A 85/4885NISCH 2195/4885 |
| US-20130225808-A1 | PHENYLACETIC ACID COMPOUND | PC, PAH, PDHA2 | CASR 4358/4885HTR1A 117/4885NISCH 1687/4885 |
| US-20060089353-A1 | Indole derivative compounds and drugs containing the compounds as the active ingredient | PTGIS, IDO1, IDO2 | CASR 1035/4885HTR1A 223/4885NISCH 2741/4885 |
| US-20050004096-A1 | Indole derivatives, process for producing the same and drugs containing the same as the active ingredient | IDO1, IDO2, PTGIR | CASR 718/4885HTR1A 50/4885NISCH 1449/4885 |
| US-20130028887-A1 | PHENYLACETIC ACID COMPOUND | PC, PAH, PDHA2 | CASR 4358/4885HTR1A 117/4885NISCH 1687/4885 |
| US-20050222216-A1 | Carboxyoic acid compounds and drugs containing the compounds as the active ingredient | UACA, CPA3, HCAR1 | CASR 231/4885HTR1A 461/4885NISCH 2753/4885 |
| US-20140357630-A1 | Phenylacetic Acid Compound | PC, PAH, PDHA2 | CASR 4358/4885HTR1A 117/4885NISCH 1687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.