Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11503610 | 0.83 | ALOX5 (0.32) | SMN1; SMN2PTGS2 | |
| SCHEMBL7312733 | 0.81 | SMN1; SMN2 (0.32) | SMN1; SMN2KDM4EALDH1A1MAPK1 | |
| SCHEMBL18706209 | 0.81 | TAAR1 (0.32) | SMN1; SMN2KDM4EALDH1A1MAPK1 | |
| SCHEMBL7772526 | 0.81 | NQO1 (0.36) | ALDH1A1 | |
| SCHEMBL18705840 | 0.81 | SMN1; SMN2 (0.32) | SMN1; SMN2KDM4EALDH1A1MAPK1 | |
| SCHEMBL1552343 | 0.80 | ALOX5 (0.37) | SMN1; SMN2PTGS2 | |
| SCHEMBL11503560 | 0.79 | ADRA2A (0.30) | — | |
| SCHEMBL18705611 | 0.79 | HTR7 (0.36) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL57641 | 0.78 | ALDH1A1 (0.41) | SMN1; SMN2KDM4EALDH1A1MAPK1 | |
| SCHEMBL177278 | 0.78 | GABRA1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1219752-C | Process for preparing substituted hydrazide by using carboxylic acid | DOW AGROSCIENCES LLC (US) | 2005-09-21 | — | — | CN | claimed |
| EP-0986560-B1 | PYRROLO 2,1,5-CD]INDOLIZINE DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES | KAROBIO AB (SE) | 2004-03-24 | — | — | EP | claimed |
| CN-1248576-A | Process for preparing substituted hydrazide by using carboxylic acid | ROHM & HAAS (US) | 2000-03-29 | — | — | CN | claimed |
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |
| US-10077254-B2 | Tetrazolinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-09-18 | — | — | US | disclosed |
| EP-3045450-B1 | INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS | SUMITOMO CHEMICAL CO (JP) | 2018-02-07 | — | — | EP | disclosed |
| EP-3059233-B1 | TETRAZOLINONE COMPOUND AND APPLICATION FOR SAME | SUMITOMO CHEMICAL CO (JP) | 2017-12-20 | — | — | EP | disclosed |
| CN-104245689-B | Terazololine-one compound and its purposes as insecticide | 住友化学株式会社 | 2017-06-06 | — | — | CN | disclosed |
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |
| US-20160272622-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-09-22 | — | — | US | disclosed |
| CN-104326952-B | Prepare method and its intermediate of pyridazinone compound | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |
| CN-100564383-C | Organosilicon compound and manufacture method thereof | SUMITOMO CHEMICAL CO (JP) | 2009-12-02 | — | — | CN | disclosed |
| CN-1930174-A | Organosilicon compound and method for producing same | SUMITOMO CHEMICAL CO (JP) | 2007-03-14 | — | — | CN | disclosed |
| CN-1219752-C | Process for preparing substituted hydrazide by using carboxylic acid | DOW AGROSCIENCES LLC (US) | 2005-09-21 | — | — | CN | disclosed |
| CN-1114602-C | Ketone derivatives and medicinal use thereof | TORAY INDUSTRIES (JP) | 2003-07-16 | — | — | CN | disclosed |
| EP-1115700-A1 | OPTICALLY ACTIVE SUBSTITUTED N-ARYL-O-ARYLOXYALKYL-CARBAMATES | BAYER AG (DE) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017157-A1 | OPTICALLY ACTIVE SUBSTITUTED N-ARYL-O-ARYLOXYALKYL-CARBAMATES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-30 | — | — | WO | disclosed |
| CN-1248576-A | Process for preparing substituted hydrazide by using carboxylic acid | ROHM & HAAS (US) | 2000-03-29 | — | — | CN | disclosed |
| CN-1242771-A | Ketone derivatives and medicinal use thereof | TORAY INDUSTRIES (JP) | 2000-01-26 | — | — | CN | disclosed |
| US-4169106-A | Antiarrhythmic N,N'-bis(phenylcarbamoylalkyl)amidines | COOPER LABORATORIES, INC. (US) | 1979-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10077254-B2 | Tetrazolinone compound and use thereof | MT-CO1, UQCRB, MT-CO2 | SMN1; SMN2 1886/4885KDM4E 2469/4885ALDH1A1 1465/4885 |
| US-20160272622-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | MT-CO1, UQCRB, MT-CO2 | SMN1; SMN2 1886/4885KDM4E 2469/4885ALDH1A1 1465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.