Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 11/20 | 0.38 |
| ▸ | MMP9 | P14780 | 9/20 | 0.38 |
| ▸ | MMP2 | P08253 | 9/20 | 0.38 |
| ▸ | MMP14 | P50281 | 8/20 | 0.38 |
| ▸ | MMP8 | P22894 | 7/20 | 0.38 |
| ▸ | MMP12 | P39900 | 7/20 | 0.38 |
| ▸ | MMP16 | P51512 | 7/20 | 0.38 |
| ▸ | MMP3 | P08254 | 7/20 | 0.38 |
| ▸ | MMP1 | P03956 | 7/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323399 | 0.89 | MMP9 (0.49) | MMP13MMP9MMP2MMP14MMP8 | |
| SCHEMBL7316684 | 0.89 | MMP9 (0.46) | MMP13MMP9MMP2MMP14MMP8 | |
| SCHEMBL7317445 | 0.88 | MMP13 (0.45) | CNR2MMP13MMP9MMP2MMP14 | |
| SCHEMBL7319249 | 0.86 | MMP13 (0.43) | MMP13MMP9MMP2MMP14MMP8 | |
| SCHEMBL7317152 | 0.85 | MMP1 (0.38) | MMP13MMP9MMP2MMP14MMP8 | |
| SCHEMBL7325505 | 0.82 | MMP9 (0.46) | MMP13MMP9MMP2MMP14MMP8 | |
| SCHEMBL7316165 | 0.82 | MMP9 (0.48) | MMP13MMP9MMP2MMP14MMP8 | |
| SCHEMBL7319004 | 0.82 | MMP9 (0.48) | MMP13MMP9MMP2MMP14MMP8 | |
| SCHEMBL7321847 | 0.81 | MMP13 (0.44) | MMP13MMP9MMP2MMP14MMP8 | |
| SCHEMBL7310752 | 0.81 | MMP9 (0.47) | MMP13MMP9MMP2MMP14MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |