Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.38 |
| ▸ | MMP9 | P14780 | 5/20 | 0.38 |
| ▸ | MMP13 | P45452 | 5/20 | 0.38 |
| ▸ | MMP2 | P08253 | 4/20 | 0.38 |
| ▸ | MMP3 | P08254 | 4/20 | 0.38 |
| ▸ | MMP12 | P39900 | 4/20 | 0.38 |
| ▸ | MMP14 | P50281 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 3/20 | 0.36 |
| ▸ | MMP16 | P51512 | 3/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316889 | 0.89 | MMP1 (0.41) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL7323399 | 0.88 | MMP9 (0.49) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL7315601 | 0.88 | PLA2G2A (0.47) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL7316684 | 0.87 | MMP9 (0.46) | MMP1MMP9MMP13MMP2MMP14 | |
| SCHEMBL7317445 | 0.86 | MMP13 (0.45) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL7313417 | 0.85 | CNR2 (0.39) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL7319249 | 0.84 | MMP13 (0.43) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL7325505 | 0.80 | MMP9 (0.46) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL7316165 | 0.80 | MMP9 (0.48) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL7319004 | 0.80 | MMP9 (0.48) | MMP1MMP9MMP13MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |