Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311139 | 1.00 | EBP (0.43) | EBPSIGMAR1L3MBTL1CYP3A4ABCB1 | |
| SCHEMBL7315211 | 0.93 | POLB (0.39) | EBPSIGMAR1L3MBTL1CYP3A4ABCB1 | |
| SCHEMBL7314600 | 0.93 | GPR139 (0.39) | EBPSIGMAR1L3MBTL1CYP3A4ABCB1 | |
| SCHEMBL7309023 | 0.91 | CYP3A4 (0.42) | EBPSIGMAR1CYP3A4ABCB1CYP3A5 | |
| SCHEMBL7308820 | 0.91 | CYP3A4 (0.38) | EBPSIGMAR1L3MBTL1CYP3A4ABCB1 | |
| SCHEMBL7309649 | 0.89 | MTNR1A (0.43) | CYP3A4ABCB1CYP3A5ADRA1ACACNA1B | |
| SCHEMBL7309344 | 0.86 | L3MBTL1 (0.37) | L3MBTL1CYP3A4HPGDALDH1A1ADRA1D | |
| SCHEMBL7314922 | 0.83 | EBP (0.43) | EBPSIGMAR1L3MBTL1CYP3A4ABCB1 | |
| SCHEMBL7313591 | 0.83 | CCR1 (0.39) | HPGDALDH1A1ADRA1DADRA1AADRA1B | |
| SCHEMBL7305541 | 0.82 | EBP (0.43) | EBPSIGMAR1L3MBTL1CYP3A4ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |