Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | MMP9 | P14780 | 4/20 | 0.39 |
| ▸ | MMP13 | P45452 | 4/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.39 |
| ▸ | HTR6 | P50406 | 8/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316642 | 0.91 | MMP9 (0.48) | MMP1MMP9MMP13ADAM17HTR6 | |
| SCHEMBL7316354 | 0.79 | NAMPT (0.42) | MMP1MMP9MMP13LMNA | |
| SCHEMBL7351590 | 0.75 | MMP9 (0.41) | MMP1MMP9MMP13ADAM17HTR6 | |
| SCHEMBL7316231 | 0.75 | MMP1 (0.44) | MMP1MMP9MMP13ADAM17HTR6 | |
| SCHEMBL7322465 | 0.74 | MMP2 (0.37) | MMP1MMP9MMP13ADAM17L3MBTL1 | |
| SCHEMBL7321295 | 0.74 | MMP9 (0.49) | MMP1MMP9MMP13ADAM17HTR6 | |
| SCHEMBL7313738 | 0.72 | NAMPT (0.43) | MMP1MMP9MMP13ADAM17 | |
| SCHEMBL7315190 | 0.71 | MMP9 (0.46) | MMP1MMP9MMP13ADAM17 | |
| SCHEMBL7313719 | 0.70 | MMP9 (0.59) | MMP1MMP9MMP13ADAM17HTR6 | |
| SCHEMBL7323234 | 0.69 | MMP1 (0.44) | MMP1MMP9MMP13ADAM17HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |