Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 17/20 | 0.48 |
| ▸ | MMP13 | P45452 | 17/20 | 0.48 |
| ▸ | MMP1 | P03956 | 16/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 15/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | MMP16 | P51512 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313728 | 0.91 | MMP1 (0.39) | MMP9MMP13MMP1ADAM17HTR6 | |
| SCHEMBL7321295 | 0.83 | MMP9 (0.49) | MMP9MMP13MMP1ADAM17HTR6 | |
| SCHEMBL7315190 | 0.80 | MMP9 (0.46) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7315622 | 0.77 | MMP13 (0.46) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL7316400 | 0.77 | MMP9 (0.54) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL7351590 | 0.75 | MMP9 (0.41) | MMP9MMP13MMP1ADAM17HTR6 | |
| SCHEMBL7325394 | 0.75 | MMP13 (0.56) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL7322465 | 0.74 | MMP2 (0.37) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL7316636 | 0.72 | MMP9 (0.73) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7313738 | 0.72 | NAMPT (0.43) | MMP9MMP13MMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |