Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 2/20 | 0.40 |
| ▸ | CCR2 | P41597 | 11/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7315970 | 0.93 | CCR2 (0.41) | ABCB11CCR2PLA2G2AGRIN1GRIN2B | |
| Trifluoroacetic Acid SCHEMBL7318205 | 0.87 | ICMT (0.41) | PLA2G2AGRIN1GRIN2B | |
| Trifluoroacetic Acid SCHEMBL7312753 | 0.83 | MDM2 (0.39) | PLA2G2AGRIN1GRIN2BPTGES2PTGES | |
| Trifluoroacetic Acid SCHEMBL7585777 | 0.72 | EGFR (0.46) | PLA2G2A | |
| Trifluoroacetic Acid SCHEMBL7402879 | 0.72 | KDM1A (0.33) | GRIN1GRIN2B | |
| Trifluoroacetic Acid SCHEMBL7321085 | 0.70 | EGFR (0.47) | PLA2G2A | |
| Trifluoroacetic Acid SCHEMBL7400482 | 0.66 | HCRTR1 (0.36) | — | |
| Trifluoroacetic Acid SCHEMBL6379652 | 0.66 | TAAR1 (0.68) | — | |
| Trifluoroacetic Acid SCHEMBL7320998 | 0.65 | EGFR (0.47) | PLA2G2A | |
| Trifluoroacetic Acid SCHEMBL7307520 | 0.64 | PTGDR2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | claimed |
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | claimed |
| US-20020004198-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2002-01-10 | — | — | US | disclosed |
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | CTSL, MMP8, SERPINB1 | ABCB11 1769/4885CCR2 384/4885PLA2G2A 2102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.